Fluoride containing mouth rinses, dentifrices, and gels

Drug – bio-affecting and body treating compositions – Dentifrices – Fluorine or fluorine compound containing

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Details

424673, 424674, A61K 718, A61K 3316

Patent

active

051456680

ABSTRACT:
Previous mouthwashes and dentifrices containing fluoride contributed relatively modest amounts of additional fluoride to the tooth surfaces, and scavenged calcium from the teeth. The present invention can deposit significantly more fluoride in the mouth than previously used formulations containing comparable amounts of fluoride, without scavenging calcium from the teeth. The invention includes a method of fluoridating teeth comprising (1) mixing in an aqueous environment a first component comprising a stable, non-toxic soluble calcium salt with a second component comprising a stable, non-toxic readily hydrolyzable complex fluoride compound, resulting in hydrolysis of the fluoride compound and precipitation of calcium fluoride, followed by (2) prompt application of the mixture to tooth surfaces. The invention also contemplates mouth rinses, denifrices, gels or pastes, and chewable tablets for application of the above-described compositions.

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patent: 4861590 (1989-08-01), Grodberg

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