Fluoride-containing Bioglass.TM. compositions

Compositions: ceramic – Ceramic compositions – Devitrified glass-ceramics

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501 1, 501 57, 623 16, 128 92R, 428432, C03C 1000

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active

047756462

ABSTRACT:
A fluoride-containing bioactive glass composition suitable for bulk implant prosthetic devices and coatings for prosthetic devices, the bioactive glass compositions selected from glass formulations containing, by mole 46.1% SiO.sub.2, 2.6% P.sub.2 O.sub.5, 26.9% CaO and 24.4% Na.sub.2 O and glass formulations containing, by mole, 52.1% SiO.sub.2, 23.8% CaO, 21.5% Na.sub.2 O, 2.6% P.sub.2 O.sub.5 wherein, respectively, 30 to 50 molar percent and 40 to 60 molar percent of the CaO is substituted with CaF.sub.2. These fluoride-containing bioactive glass materials demonstrate high resistance to demineralization in physiological fluids as well as extensive apatite formation which shows a predominance of crystalline apatite of mixed phase character.

REFERENCES:
patent: 3922155 (1975-11-01), Broemer et al.
patent: 3981736 (1976-09-01), Broemer et al.
patent: 4103002 (1978-07-01), Hench et al.
patent: 4159358 (1979-06-01), Hench et al.
patent: 4234972 (1980-11-01), Hench et al.
Hench et al., J. Biomedical Material Res. Symposium, No. 4, pp. 25-42 (1973).

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