Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2007-05-15
2007-05-15
Nashed, Nashaat T. (Department: 1656)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C435S006120, C435S069100, C435S252300, C435S320100, C536S023500, C436S164000
Reexamination Certificate
active
10315920
ABSTRACT:
Fluorescent timer proteins, which undergo a spectral shift over time after synthesis, as well as nucleic acid compositions encoding the same, are provided. Also provided are fragments of the subject proteins and nucleic acids encoding the same, as well as antibodies to the subject proteins and transgenic cells and organisms including the subject nucleic acid molecules. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in such applications that include the subject nucleic acid compositions are provided.
REFERENCES:
patent: 6969597 (2005-11-01), Lukyanov et al.
patent: 2002/0160473 (2002-10-01), Lukyanov et al.
patent: 2002/0197676 (2002-12-01), Lukyanov et al.
patent: 2004/0171107 (2004-09-01), Nelson et al.
patent: 2005/0032085 (2005-02-01), Labas et al.
patent: 2006/0035330 (2006-02-01), Lukyanov et al.
patent: WO 00/34326 (2000-06-01), None
Baird et al. Biochemistry, mutagenesis and oligomerization of Dsred, a red fluorescent protein from coral. Oct. 24, 2000. Proc. Natl. Acad. Sci., USA 97 (22) :11984-11989.
Labas et al. Diversity and evolution of the green fluorescent protein family, Apr. 2, 2002. Proc. Nat. Acad. Sci., USA 99(7): 4256-4261.
Cormack et al. FACS-optimized mutants of the green fluorescent protein (GFP)Gene173 (996) 33-38.
Matz et al. “Fluorescent proteins from nonbioluminescent Anthozoa species”Nature Biotechnology,vol. 17, Oct. 1999 pp. 969-973.
Ormo et al “Crystal structure of theAequorea victoriaGreen Fluorescent Protein”Sciencevol. 273, Sep. 6, 1996, pp. 1392-1395.
Tsien et al “The Greeen Fluorescent Protein”Annu. Rev. Biochem,1998, 67:609-44.
Terskikh et al. “Fluorescent Timer”: Protein that changes color with time,Science,vol. 290, Nov. 24, 2000.
Fradkov Arcady Fedorovich
Terskikh Alexey
Bozicevic Field & Francis LLP
Clontech Laboratories, Inc.
Field Bret E.
Moore William W.
Nashed Nashaat T.
LandOfFree
Fluorescent timer proteins and methods for their use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorescent timer proteins and methods for their use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent timer proteins and methods for their use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3728846