Fluorescent thyroid hormone conjugates and their uses

Details Fluorescent thyroid hormone conjugates and their uses Fluorescent thyroid hormone conjugates and their uses

1980-01-11

1982-05-11

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424 8, 544300, 549388, 549223, C07D40512, A61K 31495

Patent

active

043294618

ABSTRACT:
Novel polyhalothyronines or immunogenic mimetic analogs are provided conjugated to a fluorescer compound with the resulting conjugate being highly fluorescent. Specifically, the compounds have at least one of the following characteristics: bromine(s) at the 3',5'-positions of the thyronine or mimetic analog; or a rigid linking group between the thyronine and the fluorescer, so as to inhibit heavy atom catalyzed decay of fluorescence. The subject conjugates find a wide variety of uses in detecting for thyroid hormones as well as proteins which specifically bind to thyroid hormones.

REFERENCES:
patent: 3200120 (1965-08-01), Lovell
patent: 3901645 (1975-08-01), Gross
patent: 3992631 (1976-11-01), Harte
patent: 3996345 (1976-12-01), Ullman et al.
patent: 3998943 (1976-12-01), Ullman
patent: 4067959 (1978-01-01), Bolz
patent: 4160818 (1979-07-01), Smith et al.

Affiliated with

Also associated with

Rating

Fluorescent thyroid hormone conjugates and their uses does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fluorescent thyroid hormone conjugates and their uses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent thyroid hormone conjugates and their uses will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-756969