Fluorescent somatostatin

Details Fluorescent somatostatin Fluorescent somatostatin

1995-04-04

1997-12-02

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Somatostatin ; related peptides

435 71, C07K 700

Patent

active

056936796

ABSTRACT:
Light-emitting compounds of the formula: ##STR1## where R.sub.1 is a light-emitting moiety and R.sub.2 is a somatostatin-based peptide featuring a first amino acid sequence --Phe--Phe--Trp--Lys--Thr-- (SEQ ID NO:1) or --Phe--Phe--D--Trp--Lys--Thr--. The peptide is linked at a first amino acid position to (C--X), and the light-emitting compound exhibits substantial biological activity in the presence of a receptor having affinity for somatostatin-based peptides.

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