Fluorescent somatostatin

Details Fluorescent somatostatin Fluorescent somatostatin

1995-06-07

1998-10-20

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Somatostatin ; related peptides

435 71, C07K 1500

Patent

active

058247726

ABSTRACT:
Light-emitting compounds of the formula: ##STR1## where R.sub.1 is a light-emitting moiety and R.sub.2 is a somatostatin-based peptide featuring a first amino acid sequence -Phe-Phe-Trp-Lys-Thr- or (SEQ ID NO:1) or -Phe-Phe-D-Trp-Lys-Thr-. The peptide is linked at a first amino acid position to (C-X), and the light-emitting compound exhibits substantial biological activity in the presence of a receptor having affinity for somatostatin-based peptides.

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