Chemistry: analytical and immunological testing – Metal or metal containing – Present in biological fluids
Reexamination Certificate
2009-09-22
2011-11-22
Hill, Jr., Robert J (Department: 1777)
Chemistry: analytical and immunological testing
Metal or metal containing
Present in biological fluids
C436S081000, C422S082080
Reexamination Certificate
active
08062893
ABSTRACT:
The present invention provides a sensor for detecting mercury, comprising: a first polynucleotide, comprising a first region, and a second region, a second polynucleotide, a third polynucleotide, a fluorophore, and a quencher, wherein the third polynucleotide is optionally linked to the second region; the fluorophore is linked to the first polynucleotide and the quencher is linked to the second polynucleotide, or the fluorophore is linked to the second polynucleotide and the quencher is linked to the first polynucleotide; the first region and the second region hybridize to the second polynucleotide; and the second region binds to the third polynucleotide in the presence of Hg2+ions.
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Lee Jung Heon
Lu Yi
Wang Zidong
Gerido Dwan A
Hill, Jr. Robert J
Klarquist & Sparkman, LLP
The Board of Trustees of the University of Illinois
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