Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2011-03-01
2011-03-01
Riley, Jezia (Department: 1637)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S025300, C536S026600, C536S023100, C435S006120
Reexamination Certificate
active
07897736
ABSTRACT:
Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group.
REFERENCES:
patent: 2264303 (1941-12-01), Dickey
patent: 3407189 (1968-10-01), Merian
patent: 4358535 (1982-11-01), Falkow et al.
patent: 4868105 (1989-09-01), Urdea et al.
patent: 4954630 (1990-09-01), Klein et al.
patent: 5124246 (1992-06-01), Urdea et al.
patent: 5210015 (1993-05-01), Gelfand et al.
patent: 5272259 (1993-12-01), Claussen et al.
patent: 5304645 (1994-04-01), Klein et al.
patent: 5328824 (1994-07-01), Ward
patent: 5451463 (1995-09-01), Nelson et al.
patent: 5455157 (1995-10-01), Hinzpeter et al.
patent: 5492806 (1996-02-01), Drmanac et al.
patent: 5502177 (1996-03-01), Matteucci et al.
patent: 5512667 (1996-04-01), Reed et al.
patent: 5525464 (1996-06-01), Drmanac et al.
patent: 5556752 (1996-09-01), Lockhart et al.
patent: 5696251 (1997-12-01), Arnold, Jr. et al.
patent: 5801155 (1998-09-01), Kutyavin et al.
patent: 5824796 (1998-10-01), Petrie et al.
patent: 5830653 (1998-11-01), Froehler et al.
patent: 5846726 (1998-12-01), Nadeau
patent: 5876930 (1999-03-01), Livak et al.
patent: 5942610 (1999-08-01), Nelson et al.
patent: 5952202 (1999-09-01), Aoyagi et al.
patent: 6007992 (1999-12-01), Lin et al.
patent: 6028183 (2000-02-01), Lin et al.
patent: 6114518 (2000-09-01), Pitner et al.
patent: 6117986 (2000-09-01), Nardone et al.
patent: 6312894 (2001-11-01), Hedgpeth et al.
patent: 6323337 (2001-11-01), Singer et al.
patent: 6399392 (2002-06-01), Haugland et al.
patent: 6416953 (2002-07-01), Heller
patent: 6448407 (2002-09-01), Lee et al.
patent: 6465175 (2002-10-01), Horn et al.
patent: 6465644 (2002-10-01), Yan et al.
patent: 6485901 (2002-11-01), Gildea et al.
patent: 6531581 (2003-03-01), Nardone et al.
patent: 1 394 368 (1975-05-01), None
patent: 1 533 121 (1978-11-01), None
patent: WO 90/14353 (1990-11-01), None
patent: WO 92/10588 (1992-06-01), None
patent: WO 96/17957 (1996-06-01), None
patent: WO 97/29154 (1997-08-01), None
patent: WO 97/39008 (1997-10-01), None
patent: WO 99/40226 (1999-08-01), None
patent: WO 99/51621 (1999-10-01), None
patent: WO 99/64431 (1999-12-01), None
patent: WO 00/06711 (2000-02-01), None
patent: WO 00/70685 (2000-11-01), None
Dawson, “The Structure and Properties of Disperse Dyes in Polyester Coloration,”JSDC, vol. 99, Jul./Aug. 1983, pp. 183-191.
Lee et al., “Seven-Color, Homogeneous Detection of Six PCR Products,”Bio Techniques, vol. 27, No. 2, 1999 (4 pgs.).
Milesi, “Synthesis of Oligonucleotide Conjugates in Anhydrous Dimethylsulfoxide,”Methods in Enzymology, Nov. 1999 (8 pgs.).
Asanuma et al., “Photo-Responsive Oligonucleotides Carrying Azobenzene in the Side-Chains,”Tetrahedron Letters, vol. 39, 1998, pp. 9015-9018.
Young et al., Quantitative Analysis of Solution Hybridisation, (Edited by Hames and Higgins),IRL Press, 1985, pp. 47-111.
Sokol et al., “Real Time Detection of DNA-RNA Hybridization in Living Cells,”Proc. Nat'l. Acad. Sci., vol. 95, Sep. 1998, pp. 11538-11543.
Heesemann, “Studies on Monolayers. 2. Designed Monolayer Assemblies of Mixed Films of Surface-Active Azo Dyes,”Journal of the American Chemical Society, vol. 102, No. 7, Mar. 26, 1980, pp. 2176-2167.
Sabnis et al., “Synthesis and Application of 5-Arylazothiophene Derivatives,”The Chemical Society of Japan, Bull. Chem. Soc. Jpn., vol. 64, No. 12, pp. 3768-3770.
Sijm et al., “Aqueous Solubility, Octanol Solubility, and Octanol/Water Partition Coefficient of Nine Hydrophobic Dyes,”Environmental Toxicology and Chemistry, Vo. 18, No. 6, 1999, pp. 1109-1117.
Weaver et al., “Heterocyclic Diazo Components,”Dyes and Pigments, vol. 3, 1982, pp. 81-121.
Keil et al., “Preparation and UV/Vis Spectroscopic Characterization of N,N-Disubstituted 2-Amino-5-arylazoselenazoles and Some of Their Carbocyclic and Heterocyclic Analogues,”J. Prakt. Chem., 2000, vol. 342, No. 2, pp. 169-174.
Lyttle et al., “Alternataives to FRET: Design of Fluoroescence-Quenched Oligonucleotide Probes with Extremely High Signal/Noise Ratios,” BIOSIS Database, Accession, No. 2001:519181. See also Poster Session from12thInternational Genome Sequencing and Analysis Conferrence, Miami Beach, Florida, Sep. 12-15, 2000 (1 pg.).
Hirshberg et al., “Crystal Structure of Phosphate Binding Protein Labeled with a Coumarin Fluorophore, a Probe for Inorganic Phosphate,”Biochemistry, 1998, vol. 37, pp. 10381-10385.
Uhlmann et al., “PNA: Sysnthetic Polyamide Nucleic Acids with Unusual Binding Properties,”Angew: Chem. Int. Ed., 1998, vol. 37, pp. 2796-2823.
Mayfield et al., “Enhancing Solid Phase Synthesis by a Noncovalent Protection Strategy-Efficient Coupling of Rhodamine to Resin-Bound Peptide Nucleic Acids,”Bioorganic&Medicinal Chemistry Letters, vol. 9, 1999, pp. 1419-1422.
Seela et al., “Duplex Stability of Pyrazolo[3,4-d]Pyrimidine DNA with Bulky 7-Substituents or Lipophilic Side Chains,” XIII International Round Table, Nucleosides, Nucleotides and Their Biological Applications, Montpellier, France, Sep. 6-10, 1998, Poster 279 (1 pg.).
Bolli et al., “Watson-Crick Base-Pairing Properties of Bicyclo-DNA,”Nucleic Acids Research, 1996, vol. 24, No. 23, pp. 4665-4672.
Huang et al., “X-Ray and1H NMR Studies of the Conformational Equilibria of 2-Z-3-Phenyl-1,3,2-Oxazaphosphorinanes. Steric and Stereoelectronic Influences on the Unexpected Axial Preferences of Me2N and MeNH Substituents on Three-Coordinate Phosphorus,”J. Org. Chem., 1993, vol. 58, pp. 6235-6246.
Boger et al., “Studies on the Total Synthesis of CC-1065: Preparation of a Synthetic, Simplified 3-Carbamoyl-1,2-dihydro-3H-Pyrrolo[3,2-e]Indole Dimer/Trimer/Tetramer (CDPI Dimer/Trimer/Tetramer) and Development of Methodology for PDE-I Dimer Methyl Ester Formation,”J. Org. Chem., 1987, vol. 52, pp. 1521-1530.
Wittwer et al., “The LightCycler™: A Microvolume Multisample Fluorimeter with Rapid Temperature Control,”BioTechniques, vol. 22, No. 1, 1997, pp. 176-181.
Holland et al., “Detection of Specific Polymerase Chain Reaction Product by Utilizing the 5′ → 3′ Exonuclease Activity ofThermus aquaticusDNA Polymerase,”Proc. Natl. Acad. Sci. USA, vol. 88, Aug. 1991, pp. 7276-7280.
Baker et al., “Fluorescent Reagents. Acyl Chlorides and Acyl Hydrazides.”J. Chem. Soc., 1950, pp. 170-173.
Forchiassin et al., “An Efficient Snythesis of Trans-Hexahydrochroman-7-One,”J. Heterocyclic Chem., vol. 20, 1983, pp. 493-494.
Seela et al., “Synthesis of Oligonucleotides Containing Pyrazolo[3,4-d]-Pyrimidines: The Influence of 7-Substituted 8-Aza-7-Deazaadenines on the Duplex Structure and Stability,”J. Chem. Soc., Perkin Trans., vol. 1, 1999, pp. 479-488.
Cardullo et al., “Detection of Nucleic Acid Hybridization by Nonradiative Fluorescence Resonance Energy Transfer,”Proc. Natl. Acad. Sci. USA, vol. 85, Dec. 1988, pp. 8790-8794.
Nielsen et al., “Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide,”Science, vol. 254, 1991, pp. 1497-1500.
Demidov et al., “Kinetics and Mechanism of Polyamide (“Peptide”) Nucleic Acid Binding to Duplex DNA,”Proc. Natl. Acad. Sci. USA, vol. 92, Mar. 1995, p. 2637-2641.
Ibrahim et al., “The Potential of 5′ Nuclease PCR for Detecting a Single-Base Polymorphism in Orthopoxvirus,”Molecular and Cellular Probes, 1997, vol. 11, pp. 143-147.
Matayoshi et al., “Novel Fluorogenic Substrates for Assaying Retroviral Proteases by Resonance Energy Transfer,”Science, vol. 247, 1990, pp. 954-958.
Wiegant et al., “Multiple and Sensitive Fluorescence in Situ Hybridization with Rhodamine-, Fluorescein-, and Coumarin-Labeled DNAs,”Cytogenet Cell Genet, vol. 63, 1993, pp. 73-76.
Eisen et al., “DNA Arrays f
Dempcy Robert O.
Gall Alexander A.
Lukhtanov Eugeny Alexander
Reed Michael W.
Vermeulen Nicolaas M. J.
Borrelli Sara K.
Elitech Holding B.V.
Jackson Walker L.L.P.
Riley Jezia
LandOfFree
Fluorescent quenching detecting reagents and methods does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorescent quenching detecting reagents and methods, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent quenching detecting reagents and methods will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2696710