Fluorescent probe

Details Fluorescent probe Fluorescent probe

2011-01-11

2011-01-11

Dentz, Bernard (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C540S222000, C549S220000, C549S388000, C435S018000, C435S019000, C435S021000

Reexamination Certificate

active

07868147

ABSTRACT:
A fluorescent probe which is represented by the following formula (I):(wherein, R1represents a monovalent substituent other than hydrogen atom, carboxy group, or sulfo group; R2represents hydrogen atom, or a monovalent substituent; R3and R4each independently represents hydrogen atom or a halogen atom; and R5represents a monovalent group which is cleaved by contact with a measuring object, provided that a combination of R1and R2is selected so that the oxidation potential of the benzene ring to which they bind makes (1) the compound represented by the formula (I) substantially no fluorescent before the cleavage, and (2) a compound after the cleavage, which is derived from the compound represented by the formula (I), substantially highly fluorescent after the cleavage).

REFERENCES:
patent: 5874590 (1999-02-01), Nagano et al.
patent: 6903226 (2005-06-01), Nagano et al.
patent: 7087766 (2006-08-01), Nagano et al.
patent: 7524974 (2009-04-01), Nagano et al.
patent: 7696245 (2010-04-01), Komatsu et al.
patent: 2003/0153027 (2003-08-01), Nagano et al.
patent: 2003/0162298 (2003-08-01), Nagano et al.
patent: 2004/0054195 (2004-03-01), Gao et al.
patent: 2005/0037332 (2005-02-01), Komatsu et al.
patent: 2006/0030054 (2006-02-01), Nagano et al.
patent: 2008/0249321 (2008-10-01), Nagano et al.
patent: 295 855 (1991-11-01), None
patent: 1260508 (2002-11-01), None
patent: 10-226688 (1998-08-01), None
patent: 01/62755 (2001-08-01), None
patent: 01/64664 (2001-09-01), None
patent: 2004/005917 (2004-01-01), None
patent: 2005/085811 (2005-09-01), None
Gao et al, Analytical Chem. vol. 74, No. 24, p. 6397-6401 (2002).
D. Tadic et al., “Chiral Prodyes. Ethers and Esters of Dihydrofluorescein, Part 1: Dibenzyldihydrofluorescein (DBDF) A New Reagent”, Heterocycles, 1990, vol. 31, No. 11, pp. 1975-1982.
An English language abstract JP 10-226688, (1987).
An English language abstract WO 2004/005917, (2004).
L. Lindqvist et al., “Radiationless Transitions in Xanthene Dyes”, J. Chem. Phys., vol. 44, pp. 1711-1712 (1966).
U.S. Appl. No. 10/598,371 to Nagano et al., (2008).
“Gendaikagaku”, Dec. 2002 (No. 381), p. 44-50.
Office Action in counterpart Japanese Patent Application 2005-513726 dated Jul. 13, 2010.
Supplementary European Search Report for European Application No. 04772924.9, (2009).
Miura, Journal of American Chemical Society, (2003), vol. 125, No. 28, pp. 8666-8671.
Fogl, J. et al., Scientific Papers of the Prague Institute of Chemical Technology. Chemical Engineering, (1981), vol. H-16, pp. 17-39.
Fedin, A. et al., Kristoallografia, (1975), vol. 20, No. 1, pp. 163-166.

Affiliated with

Also associated with

Rating

Fluorescent probe does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fluorescent probe, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent probe will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2686215