Chemistry: analytical and immunological testing – Nitrogen containing – Urea or blood urea nitrogen
Patent
1997-08-05
1999-08-31
Wallenhorst, Maureen M.
Chemistry: analytical and immunological testing
Nitrogen containing
Urea or blood urea nitrogen
436106, 436113, 436164, 436169, 436170, 436172, 436800, 422 55, 422 56, 422 8205, 422 8208, 422 8211, G01N 3300
Patent
active
059453435
ABSTRACT:
The present invention provides a urea sensor material having a first layer of a protonated pH sensitive fluorophore immobilized in a hydrophobic polymer, wherein the fluorophore can react quantitatively with ammonia and the transducing moiety of the fluorophore is neutrally charged when deprotonated; a second layer of urease and a polymer; and a third layer of a polymer. The present invention also provides a method for detecting urea using the urea sensor material and optical sensing devices that incorporate the urea sensor material.
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Bayer Corporation
Gagnebin , III Charles L.
Morgenstern Arthur S.
Wallenhorst Maureen M.
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