Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Reexamination Certificate
2006-10-17
2006-10-17
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
C435S006120, C435S007100, C435S007720, C435S091100, C436S172000, C436S501000, C436S094000, C536S023100
Reexamination Certificate
active
07122383
ABSTRACT:
A chemical composition including a fluorescent polymer and a receptor that is specific for both a target biological agent and a chemical moiety including (a) a recognition element, (b) a tethering element, and (c) a property-altering element is disclosed. Both the fluorescent polymer and the receptor are co-located on a support. When the chemical moiety is bound to the receptor, the property-altering element is sufficiently close to the fluorescent polymer to alter the fluorescence emitted by the polymer. When an analyte sample is introduced, the target biological agent, if present, binds to the receptor, thereby displacing the chemical moiety from the receptor, resulting in an increase of detected fluorescence. Assays for detecting the presence of a target biological agent are also disclosed.
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Jones Robert M.
Kumaraswamy Sriram
Ley Kevin
Lu Liangde
McBranch Duncan
Davis Deborah A.
DLA Piper (US) LLP
Le Long V.
QTL Biosystems LLC
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