Fluorescent polarization immunoassays

Details Fluorescent polarization immunoassays Fluorescent polarization immunoassays

1982-06-30

1985-01-08

Turk, Arnold

Chemistry: analytical and immunological testing

Involving immune complex formed in liquid phase

Signal modification or steric inhibition

436536, 436800, 436825, G01N 3354

Patent

active

044927622

ABSTRACT:
Improvement in fluorescent polarization immunoassays for substances in blood plasma or serum comprising conducting the assays in dilute anionic surfactant solutions which disrupt the fluorescent bilirubin serum albumin complex without disturbing the antibody reaction in the immunoassay. In this manner, background fluorescence in icteric samples is greatly reduced.

REFERENCES:
patent: 4115699 (1978-09-01), Mizuta et al.
patent: 4204839 (1980-05-01), Wu et al.
patent: 4252783 (1981-02-01), Kam et al.

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