Fluorescent membrane intercalating probes and methods for...

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Diagnostic or test agent produces in vivo fluorescence

Reexamination Certificate

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C424S001110, C424S001650, C424S009100

Reexamination Certificate

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08029767

ABSTRACT:
The invention relates to a family of cyanine dyes which fluoresce in the far red and near infra red wavelengths of the spectrum and preferably possess lipophilic side chains. The dyes of the invention are soluble in commercially available membrane staining vehicles, are useful as probes for rapidly staining lipophilic structures such as membranes in cells or isolated from cells, and are well retained therein. Methods of using the dyes to detect stained cells both in vivo and in vitro are also disclosed.

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patent: 7462347 (2008-12-01), Gray
patent: 0800831 (1997-10-01), None
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