Chemistry: analytical and immunological testing – Involving producing or treating antigen or hapten – Producing labeled antigens
Patent
1986-02-03
1987-01-20
Schwartz, Richard A.
Chemistry: analytical and immunological testing
Involving producing or treating antigen or hapten
Producing labeled antigens
556 1, 25230116, 25230117, 25230118, 424 71, 435 4, 435 7, 436800, 544 64, 546 2, 546 10, 549 3, G01N 2164
Patent
active
046379886
ABSTRACT:
There are described stable fluorescent labels comprising a complex of lanthanide metal and a chelating agent comprising a nucleus which is a triplet sensitizer having a triplet energy greater than that of said lanthanide metal and at least two heteroatom-containing groups which form coordinate complexes with lanthanide metals and a third heteroatom-containing group or heteratom in or appended to the triplet sensitizer. Labeled physiologically active materials useful in specific binding assays such as labeled antigens, heptens, antibodies, hormones and the like comprising the stable fluorescent labels having physiologically active materials adsorbed or bonded thereto are also described.
REFERENCES:
patent: 4058732 (1977-11-01), Wieder
patent: 4259313 (1981-03-01), Frank et al.
patent: 4283382 (1981-08-01), Frank et al.
patent: 4352751 (1982-10-01), Wieder et al.
Chemical Abstracts, 82:38148k (1975) [Busev, A., et al., Zh. Anal. Khim. 1974, 29(8), 1474-7].
Hinshaw Jerald C.
Reynolds George A.
Toner John L.
Eastman Kodak Company
Rosenstein Arthur H.
Schwartz Richard A.
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