Fluorescent label compounds

Details Fluorescent label compounds Fluorescent label compounds

2003-03-10

2008-12-16

Davis, Zinna N (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S183000, C540S001000, C546S257000

Reexamination Certificate

active

07465747

ABSTRACT:
It is intended to provide novel labeling reagents characterized by having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.), easily forming a complex together with a rare earth ion, the complex being stable in an aqueous solution, and having a sufficient fluorescence intensity and a long fluorescence life time regardless of buffer types; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence assay method using the above fluorescent label; etc. Namely, labeling reagents comprising a compound having a 2,2′:6′,2″-tripyridine skeleton or a 2,6-dipyrazolopyridine skeleton and having a group capable of binding to a substance to be labeled (for example, a biological substance, a physiologically active substance, etc.) and a group capable of forming a complex together with a rare earth ion; complexes composed of the above labeling reagent with a rare earth ion; fluorescence labels containing the above complex; a fluorescence labeling method using the above complex as a label; and a fluorescence assay method using the above fluorescent label.

REFERENCES:
patent: 1407052 (2003-04-01), None
patent: 1 491 629 (2004-12-01), None
patent: 1-503806 (1989-12-01), None
patent: 3-500297 (1991-01-01), None
patent: 7-506667 (1995-07-01), None
patent: 2001-335574 (2001-12-01), None
patent: WO 93/11433 (1993-06-01), None
patent: WO 03/076615 (2003-09-01), None
U.S. Appl. No. 10/506,242, filed Sep. 8, 2004, Matsumoto, et al.
U.S. Appl. No. 10/506,240, filed Sep. 8, 2004, Matsumoto, et al.
Jingli Yuan, et al., “Synthesis of a Terbium Fluorescent Chelate and its Application to Time-Resolved Fluoroimmunoassay”, Analytical Chemistry, vol. 73, No. 8, XP-001030284, Apr. 15, 2001, pp. 1869-1876.
Veli-Matti Mukkala, et al., “Development of luminescent europium (III) and Terbium (III) chelats of 2,2′:6′,2″-terpyridine derivatives for protein labelling”, Helvetica Chimica Acta, vol. 76, pp. 1361-1378 1993.

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