Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-05-30
1999-07-06
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
540472, 540474, 436501, 436800, 436536, 436518, C07D48722, C09B 4704, C07F 708, G01N 3353
Patent
active
059199229
ABSTRACT:
Fluorescent dyes which are free of aggregation and serum binding are provided. These dyes are suitable for applications such as fluorescence immunoassays, in vivo imaging and in vivo tumor therapy.
REFERENCES:
patent: 2951797 (1960-09-01), Sharp et al.
patent: 3116256 (1963-12-01), D'Alelio et al.
patent: 3287470 (1966-11-01), Pugin et al.
patent: 4104466 (1978-08-01), Tsuchida et al.
patent: 4404366 (1983-09-01), Boguslaski et al.
patent: 4614723 (1986-09-01), Schmidt et al.
patent: 4707454 (1987-11-01), Hendrix
patent: 4732570 (1988-03-01), Baumgartner et al.
patent: 4822733 (1989-04-01), Morrison et al.
patent: 4822877 (1989-04-01), Inada et al.
patent: 4849207 (1989-07-01), Sakata et al.
patent: 4877872 (1989-10-01), Morgan et al.
patent: 4886744 (1989-12-01), Arnost et al.
patent: 5053423 (1991-10-01), Liu
patent: 5059510 (1991-10-01), Jones et al.
patent: 5135717 (1992-08-01), Renzoni et al.
patent: 5177200 (1993-01-01), Kluger et al.
patent: 5378634 (1995-01-01), Shigetoh et al.
patent: 5403928 (1995-04-01), Arrhenuis
patent: 5593867 (1997-01-01), Walker et al.
Barrett et al., "Phthalocyanines and Related Coumpounds. Part XV. Tetrabenztriazaporphin: its Preparation from Phthalonitrile and a Proof of its Structure," Phthalocyanines and Related Coumpounds--Part XV, pp. 1809-1820 (1939).
Castillo, "Bis (Metilsiloxi) Ftalocianinas Silicio (IV)," Rev. Latinoamer. Quim. 10:113-116 (1979).
Devlin et al., "Homogeneous Detection of Nucleic Acids by Transient-State Polarized Fluorescence," Clin. Chem. 39/9:1939-1943 (1993).
Diamandis, "Automation of Molecular Diagnositics," Clinical Chemistry 42(1):7-8 (1996).
Grant et al. (eds), Grant & Hackh's Chemical Dictionary, 5th edition, McGraw-Hill Book Company, p. 241.
Hanack et al., "Synthesis and Properties of a New Kind of One-Dimensional Conductor. VIII. Synthesis and Characterization of trans-BIS-1-Alkynyl Substituted Silicon, Germanium, Tin Phthalocyanines and Germanium Hemiporphyrazines," Journal of Organometallic Chemistry 204:315-325 (1981).
Hartmann et al., "Polymere mit dem Zentralatom eines Macrocyclus inder Hauptkette, 2: Polykondensations-reaktionen mith Germaniumkomplexen des Phthalocyanin und meso-Tetraphenyloporphins," Die Makromolekulare Chemie 176:831-847 (1975).
Hartmann et al., "Polymers with the Central Atom of a Macrocycle in the Main Chain 2. Polycondensation Reactions with Germanium Complexes of Phthalocyanine and Meso-Tetra-Phenylporphin," Chemical Abstracts 83:4 at abstract no. 79670p (1975).
Joyner and Kenney, "Phthalocyaninosilicon Compounds," Inorganic Chemistry 1:236-238 (1962).
Kricka, "Ch. 2--Labeling," in Ligand-Binder Assays: Labels and Analytical Strategies, Marcel Dekker, Inc., New York pp. 15-51 (1985).
Leznoff and Lever editors, Phthalocyanines: Properties and Applications vol. 2, pp. 29-37 and 168-170 (1993).
Leznoff and McKeown, "Preparation of Substituted Tetrabenzotriazaporphyrins and a Tetranaphthotriazaporphyrin: A Route to Mono-meso-substituted Phthalocyanine Analogues," J. Org. Chem. 55:2186-2190 (1990).
Mashiko and Dolphin, "Ch. 21.1--Porphyrins, Hydroporphyrins, Azaporphyrins, Phthalocyanines, Corroles, Corrins and Related Macrocycles," in Multidenate Macrocyclic Ligands, pp. 813-898.
Merck Index (Rahway, J.J., Merck & Co., 1989) p. 172.
Meyer et al., "Polymere mit dem Zentralatom eines Makrocyclus in der Hauptkette; 4. Kovalenter Einbau von Aluminium-, Silicium-and Germaniumkomplexen des Phthalocyanins in Polester," Die Angewandte Macromolekulare Chemie 72:173-184 (1978).
Meyer et al., "Polymers with the Central Atom of a Macrocycle in the Main Chain. 1. Polycondensation reactions with phthalocyaninato silicon and hemiporphyrazinato germanium compounds," Chemical Abstracts 81:2 at abstract no. 152673g (1974).
Meyer et al., "Polymers with the Central Atom of a Macrocycle in the Main Chain. 4. Covalent Incorporation of Aluminum, Silicon, and Germanium Complexes of Phthalocyanine in Polyesters," Chemical Abstracts 90(14):1 at abstract no. 104387f (1979).
Moser and Thomas, Phthalocyanine Compounds, Reinhold Publishing Company, New York (1963) (Table of Contents Only).
Moser and Thomas (editors), The Phthalocyanines, CRC Press, Inc., Boca Raton, FL, vol. 1:123-127.
Seckinger, "Strand Displacement Amplification and Fluoresence Polarization," Clincal Chemistry 42(10):1720 (1996).
Sielcken et al., "Phthaloocyaninato Polysiloxanes Substituted with Crown Ether Moieties," J. Amer. Chem. Soc. 112(8):3086-3093 (1990).
Walker et al., "Strand Displacement amplification (SDA) and transient-state fluorescence polarization detection of Mycobacterium tuberculosis DNA," Clinical Chemistry 42(1):9-13 (1996).
Wilkinson et al. (editors), Comprehensive Coordination Chemistry: The Synthesis, Reactions, Properties & Applications of Coordination Compounds vol. 2--Ligands, Pergamon Press, pp. 859-870 (1987).
Meyer et al., Angew Makromol. Chemie 72 (1978) pp. 173-184.
Dandliker Walter Beach
Hsu Mao-Lin
Hyperion, Inc.
Raymond Richard L.
Sripada Pavanaram K.
LandOfFree
Fluorescent dyes free of aggregation and serum binding does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluorescent dyes free of aggregation and serum binding, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent dyes free of aggregation and serum binding will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-900056