Fluorescent dye intermediates

Details Fluorescent dye intermediates Fluorescent dye intermediates

1994-01-13

1997-04-29

Houtteman, Scott W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

536 2534, C07D31182

Patent

active

056250819

ABSTRACT:
Intermediates for fluorescent dyes based on 9-carboxyethyl-6-hydroxy-3-oxo-3H-xanthene which are useful as reporters for reporter-labeled DNA fragments are described. The intermediates are protected fluorescent dyes bearing acyloxy groups at the 3 and 9 positions and an alkoxy group at the 9 position. Deprotection of the protected fluorescent dye by treatment with aqueous ammonia regenerates free dye.

REFERENCES:
patent: 4439356 (1984-03-01), Khanna et al.

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