Fluorescent double stranded DNA binding dyes

Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

08058431

ABSTRACT:
Disclosed is a fluorescent dye comprising a benzothiazolium moiety and a pyrimidinium moiety connected by a mono-methine bridge, characterized in that (i) the 2-position of the pyrimidine carries a substituent which starts with a C-atom and (ii) the 5- and 6- positions of the pyrimidine ring are an integral part of a further aromatic ring structure as exemplified by the following:

REFERENCES:
patent: 4937198 (1990-06-01), Lee et al.
patent: 5658751 (1997-08-01), Yue et al.
patent: 2005/0233335 (2005-10-01), Wittwer et al.
patent: 425609 (1935-03-01), None
patent: 2004038038 (2004-05-01), None
Alfimov, M. et al., “Synthesis and spectroscopic studies of novel photochromic benzodithiacrown ethers and their complexes,” J. Chem. Soc., Perkin Trans. 2 (1996) 1441-1447.
Fry, D. et al., “The Reactivity of the Alkylthio-group in Nitrogen Ring Compounds. Part IV. Quaternary Salts of 4-Substituted Quinazolines,” J. Chem. Society (1960) 5062-5072.
Gromov, S. et al., “Reaction of Quinazoline Derivatives with Quaternary Salts of Heterocyclic Basis,” Chemistry of Heterocyclic Compounds 28 (1992) 559-566.
Gromov, S. et al., “Reactions of Quinazolinium Salts with Quaternary Heterocyclic Salts Yeilding 3-hetarylquinolines,” Russian Chemical Bulletin 47/6 (Jun. 1998) 1179-1185.
Moreda, W., et al., “Novel Heterocyclic Dyes as DNA Markers. Part I. Synthesis and Characterization,” Tetrahedron 53/37 (1997) 12595-12604.
Zipper, H. et al., “Investigations on DNA Intercalation and Surface Binding by SYBR Green I, its Structure Determination and Methodological Implications,” Nucleic Acids 32/12 (2004) e103.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Fluorescent double stranded DNA binding dyes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fluorescent double stranded DNA binding dyes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescent double stranded DNA binding dyes will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4302113

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.