Fluorescent DNA-Intercalating cyanine dyes including a positivel

Details Fluorescent DNA-Intercalating cyanine dyes including a positivel Fluorescent DNA-Intercalating cyanine dyes including a positivel

1995-11-09

1998-03-31

Ivy, C Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5462687, 5462691, 436800, C07D40108, C07D41308, C07D41708

Patent

active

057340587

ABSTRACT:
New intercalating cyanine dyes are provided in which the benzothiazole portion of the cyanine dye has been modified to produce dyes with improved properties for labelling nucleic acids. The fluorescent cyanine dyes have a positively charged substituent attached to the positively charged nitrogen on the benzothiazole portion of the cyanine dye.

REFERENCES:
patent: 3282932 (1966-11-01), Lincoln et al.
patent: 3437659 (1969-04-01), Larive et al.
patent: 3821205 (1974-06-01), Funia, Jr. et al.
patent: 4323362 (1982-04-01), Degen et al.
patent: 4600776 (1986-07-01), Meisel et al.
patent: 4677051 (1987-06-01), Kubodera
patent: 4751309 (1988-06-01), Daltrozzo
patent: 4847364 (1989-07-01), Mockli
patent: 4957870 (1990-09-01), Lee et al.
patent: 5321130 (1994-06-01), Yue et al.
patent: 5401847 (1995-03-01), Glazer
patent: 5410030 (1995-04-01), Yue et al.
patent: 5436134 (1995-07-01), Haughland et al.
patent: 5534416 (1996-07-01), Millard et al.
patent: 5545535 (1996-08-01), Roth
Becker, et al., J. Am. Chem. Soc. 1979, 101, 3664-3666.
Gaugain, et al., Biochemistry 1978, 17, 5071-5078.
Johnson, et al., Poster #1806 at 1992 Biophysical Society/ASBMB, Houston, TX.
Benson, et al. Nucleid Acids Research 1993, 21, 5720-5726.
Rye, et al. Nucleic Acids Research 1992, 20, 2803-2812.
Brooker, et al. JACS 1945, 67, 1889-1893.
Ambrogi, et al. Synthesis 1992, No. 7, 656-658.
Lee, et al. Cytometry 1986, No. 7, 508-517.
Chemical Abstracts No. 123: 1599968 Vol. 123, Frey et al., Cytometry, 1995, Vol. 20, No. 3, pp. 218-227.
Chemical Abstracts No. 119:67272, Vol. 119, Yue et al., WO9306482, Apr. 1, 1993.

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