Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1986-02-05
1988-09-27
Warden, Robert J.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
436528, 436529, 436546, 436800, 436805, G01N 33533, G01N 33544
Patent
active
047741910
ABSTRACT:
Fluorescent antigen conjugates are provided comprising antigens covalently bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent compounds absorbing at wavelengths in excess of 500 nm, having active functionalities for linking to the antigen. Finally, methods are provided for analyzing antigens in serum, whereby serum interference is avoided.
REFERENCES:
patent: 4351760 (1982-09-01), Khanna et al.
patent: 4481136 (1984-11-01), Khanna et al.
patent: 4588697 (1986-05-01), Khanna et al.
Khanna Pyare
Ullman Edwin F.
Barrett Carole F.
Benson Robert
Leitereg Theodore J.
Syntex (U.S.A.) Inc.
Warden Robert J.
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