Fluorescent conjugates bound to a support

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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Details

436528, 436529, 436546, 436800, 436805, G01N 33533, G01N 33544

Patent

active

047741910

ABSTRACT:
Fluorescent antigen conjugates are provided comprising antigens covalently bonded to at least one 2,7-dialiphatic substituted-9-phenyl-6-hydroxy-3H-xanthen-3-one, wherein the 1- and 8-positions are unsubstituted. Also provided are novel fluorescent compounds absorbing at wavelengths in excess of 500 nm, having active functionalities for linking to the antigen. Finally, methods are provided for analyzing antigens in serum, whereby serum interference is avoided.

REFERENCES:
patent: 4351760 (1982-09-01), Khanna et al.
patent: 4481136 (1984-11-01), Khanna et al.
patent: 4588697 (1986-05-01), Khanna et al.

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