Fluorescent conjugated polyene sterol derivatives as cell membra

Details Fluorescent conjugated polyene sterol derivatives as cell membra Fluorescent conjugated polyene sterol derivatives as cell membra

1986-05-28

1989-11-07

Shen, Cecilia

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603974, 2603975, C07J 900

Patent

active

048790699

ABSTRACT:
The present invention relates to the synthesis of conjugated polyene sterol derivatives, the compounds obtained and to their use as fluorescent probes for cellular membranes. The fluorescent probes of the present invention resemble cholesterol both structurally and in amphipathic nature. The probes of the present invention have potential for use in determining cholesterol levels and cholesterol properties and cell membrane properties and can be applied to clinical assays and diagnoses involving cholesterol.

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