Fluorescent compound, complex, reagent, and specific binding ass

Details Fluorescent compound, complex, reagent, and specific binding ass Fluorescent compound, complex, reagent, and specific binding ass

1991-12-20

1993-11-16

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Diazoamino

534560, 534561, 534643, 534653, 534657, 534702, 534727, 536 2532, 530406, 540 3, 540472, 540465, C07D25710, C07H 19073, C09D 29036

Patent

active

052625265

ABSTRACT:
A fluorescent compound, which is readily capable of forming a stable complex with a rare-earth metal ion having fluorescence with satisfactory intensity even in an aqueous system and long fluorescence lifetime when formed a complex with the rare-earth metal ion, a complex of the fluorescent compound and the rare-earth metal ion, and a labelled reagent made therefrom, together with a specific binding assay using said labelling agent.
A fluorescent compound expressed by the following formula A, typically exemplified by 2,15-diaza[3,3](2,9)-1,10-phenanthrolinophane-N.sup.2,N.sup.15 -diacetic acid. ##STR1##

REFERENCES:
patent: 4927923 (1990-05-01), Mathias et al.
Chandler, et al., J. Heterocyclic Chem. 18 599 (1981).
Alpha et al., Angew. Chem. Int. Ed. 26(3) 1987, 266-267.
Huang et al., Nippon Kagaku Kaishil 66-73, 1981.
K. C. Joshi et al, Journal of Fluorine Chemistry, vol. 13, pp. 261-265, 1979.
S. E. Livingstone et al, Aust. J. Chem., vol. 29, pp. 1845-1850, 1976.
H. Nakatani et al., The Review of Physical Chemistry of Japan, vol. 42, No. 2, pp. 103-107, 1972.
E. P. Diamandis et al, Journal of Immunological Methods, vol. 112, pp. 43-52, 1988.
G. Blasse, Chemistry of Materials, vol. 1, pp. 294-301, 1989.
S. J. Keipert, C.B. Knobler & D. J. Cram, Host-Guest Complexation, 43, Synthesis and Binding Properties of a Macrocycle Composed of Two Phenanthrolines and Two Slfonamide Units, Tetrahedron, vol. 43, No. 21, pp. 4861-4874, 1987.
M. A. Chan, A. C. Bellem & E. P. Diamandis, Time-Resolved Immunofluorometric Assay of Alpha-Fetoprotein in Serum and Amniotic Fluid, with a Novel Detection System, Clinical Chemistry, vol. 33, No. 11, pp. 2000-2003, 1987.

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