Fluorescent benzothiazole derivatives

Details Fluorescent benzothiazole derivatives Fluorescent benzothiazole derivatives

1993-11-24

1995-06-13

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548156, 548178, 536 173, C07D27768

Patent

active

054244404

ABSTRACT:
Novel benzothiazole derivatives having a fluorescence inhibiting group linked by an enzyme cleavable bond and methods for their synthesis are provided. Upon cleavage of the enzyme-cleavable bond, a strongly fluorescent reaction product is produced. These compounds may be used to detect enzymatic activity. The fluorescent reaction products are detectable at an attomolar level using a fluorometer.

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