Fluorescence scope system for dermatologic diagnosis

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

600473, 351165, A61B 500

Patent

active

060213442

ABSTRACT:
Apparatus for the diagnosis of a skin disease site by visual fluorescence inspection comprising an excitation light source for illuminating the disease site, a light guide for transmitting the excitation light directly to the disease site to generate fluorescence light and viewing goggles for processing the excitation light reflected and the fluorescence light emitted from the disease site to provide a fluorescence image of the disease site to a user. The fluorescence image is used to aid the medical assessment of skin conditions and the diagnosis of cutaneous diseases by supplementing the visual assessment of skin lesions made by the naked eye. The apparatus can be used in several modes of operation that permit the viewing of full color fluorescence images and enhanced two color images. The apparatus can also use image intensifying equipment to amplify fluorescence light so that even very weak fluorescing objects can be seen. A method for acquiring and viewing the fluorescence images is also disclosed.

REFERENCES:
patent: 3995937 (1976-12-01), Baues et al.
patent: 4045125 (1977-08-01), Farges
patent: 4134644 (1979-01-01), Marks et al.
patent: 4151411 (1979-04-01), Derderian et al.
patent: 4376889 (1983-03-01), Swift
patent: 4511222 (1985-04-01), Biren
patent: 4595262 (1986-06-01), Ogle
patent: 4718417 (1988-01-01), Kittrell et al.
patent: 4744633 (1988-05-01), Sheiman
patent: 4893898 (1990-01-01), Beard
patent: 4894547 (1990-01-01), Leffell et al.
patent: 4927222 (1990-05-01), Kamiya et al.
patent: 4957114 (1990-09-01), Zeng et al.
patent: 5028594 (1991-07-01), Carson
patent: 5144344 (1992-09-01), Takahashi et al.
patent: 5170501 (1992-12-01), White
patent: 5177509 (1993-01-01), Johansen et al.
patent: 5184156 (1993-02-01), Black et al.
patent: 5304173 (1994-04-01), Kittrell et al.
patent: 5450857 (1995-09-01), Garfield et al.
patent: 5452723 (1995-09-01), Wu et al.
patent: 5456260 (1995-10-01), Kollias et al.
patent: 5467767 (1995-11-01), Alfano et al.
patent: 5507287 (1996-04-01), Palcic et al.
patent: 5556612 (1996-09-01), Anderson et al.
patent: 5582168 (1996-12-01), Samuels et al.
patent: 5590660 (1997-01-01), MacAulay et al.
patent: 5592245 (1997-01-01), Moore et al.
patent: 5594843 (1997-01-01), O'Neill
patent: 5612540 (1997-03-01), Richards-Kortum et al.
patent: 5628310 (1997-05-01), Rao et al.
patent: 5647368 (1997-07-01), Zeng et al.
patent: 5687730 (1997-11-01), Doiron et al.
patent: 5708490 (1998-01-01), Wieczorek
Bissonnette et al., Detection of Autofluorescence Due to Protoporphyrin IX in the Stratum Corneum of Psoriasis Plaques. Abstract MPM-F10. Photochemistry and Photobiology 65(S):49S, 1997.
Cascinelli et al., A possible new tool for clinical diagnosis of melanoma: The computer. Journal of the American Academy of Dermatology, 16:361-367, 1987.
Kini and Dhawan, Three-Dimensional Imaging and Reconstruction of Skin Lesions. Computerized Medical Imaging and Graphics, 16:153-161, 1992.
Dhawan and Sicsu, Segmentation of Images of Skin Lesions Using Color and Texture Information of Surface Pigmentation. Computerized Medical Imaging Graphics, 16:163-177, 1992.
Di Carlo, Thermography and the Possibilities for Its Applications in Clinical and Experimental Dermatology, Clinics in Dermatology, 13:329-336, 1995.
Feld et al., Detection and characterization of human tissue lesions with near infrared Raman spectroscopy. SPIE Proceedings, 2388:99-104, 1995.
Green et al., Computer image analysis of pigmented skin lesions. Melanoma Research, 1:231-236, 1991.
Herbin et al., Color Quantitation Through Image Processing in Dermatology. IEEE Transactions on Medical Imaging, 9:262-269, 1990.
Jimbow et al., Melanin Pigments and Melanosomal Proteins as Differentiation Markers Unique to Normal and Neoplastic Melanocytes. Journal of Investigative Dermatology, 100:259S-268S, 1993.
Liu et al., Raman, fluorescence, and time-resolved light scattering as optical diagnostic techniques to separate diseased and normal biomedical media. Journal of Photochemistry and Photobiology B: Biology, 16:187-209, 1992.
Lui et al., Optical Spectroscopy as a Potential Diagnostic Aid for Dermatology. Clinical Dermatology 2000--An International Congress, Vancouver, BC, May 28-31, 1996, Programme and Abstracts, Abstract 584, p. 176.
Lui et al., Ratio Analysis of Reflectance and Fluorescence Spectra of Diseased Skin. 24.sup.th Annual Meeting of the American Society of Photobiology, Atlanta, Georgia, Jun. 15-20, 1996.
Owen et al., New spectroscopic instrument based on volume holographic optical elements. SPIE Proceedings, 2406:260-267, 1995.
Seidenari, High-Frequency Sonography Combined with Image Analysis: A noninvasive Objective Method for Skin Evaluation and Description. Clinics in Dermatology, 13:349-359, 1995.
Stoecker and Moss, Editorial: Digital Imaging in Dermatology. Computerized Medical Imaging and Graphics, 16:145-150, 1992.
Stoecker et al., Texture in Skin Images: Comparison of Three Methods to Determine Smoothness. Computerized Medical Imaging and Graphics, 16:179-190, 1992.
Umbaugh et al., Automatic Color Segmentation Algorithms. IEEE Engineering in Medicine and Biology, 75-82, 1993.
Zeng, Human Skin Optical Properties and Autofluorescence Decay Dynamics. Ph.D. Thesis, The University of British Columbia, Vancouver, Canada, 1993.
Zeng et al., A computerized autofluroescence and diffuse reflectance spectroanalyser system for in vivo skin studies. Physics in Medicine and Biology, 38:231-240, 1993.
Zeng et al., Autofluorescence distribution in skin tissue revealed by microspectrophotometer measurements. SPIE Proceedings, 1876:129-135, 1993.
Zeng et al., Novel Miscrospectrophotometer and its Biomedical Applications. Optical Engineering, 32:1809-1813, 1993.
Zeng et al., Laser-induced changes in autofluorescence of in vivo skin. SPIE Proceedings, 1882:278-290, 1993.
Zeng et al., Update on fluorescence spectroscopy studies of diseased skin. SPIE Proceedings, 2671E-42, 1993.
Zeng et al., Monte Carlo modeling of tissue autofluorescence measurement and imaging. SPIE Proceedings, 2135:94-104, 1994.
Zeng et al., Miniature spectrometer and multi-spectral imager as a potential diagnostic aid in dermatology. SPIE Proceedings, 2387:57-61, 1995.
Zeng et al., Miniature Spectrometer and Multi-Spectral Imager for Skin Diagnosis. Laser in Dermatology, Plastic Surgery and Burn Treatment at Biomedical Optics '95, San Jose, CA, Feb. 4-10, 1995, In: SPIE 2387-09:17, 1995.
Zeng et al., Spectroscopic and Microscopic Characteristics of Human Skin Autofluorescence Emission. Photochemistry and Photobiology, 61:639-645, 1995.
Zeng et al., Optical spectroscopy studies of diseased skin--preliminary results. SPIE Proceedings, 2628:281-285, 1995.
Zeng et al., Non-invasive, Bedside Autofluorescence Spectroscopy of Benign and Malignant Skin Lesions, abstract. Fourth Meeting of the Western Canadian Society for Clinical and Investigative Dermatology, Jasper, AB, Mar. 24-26, 1995.
Zeng et al., Optical spectroscopy studies of diseased skin, abstract. European BioMedical Optics--BIOS Europe '95, Barcelona, Spain, Sept. 12-16, 1995.
Zeng et al., Update on Fluroescence Spectroscopy Studies of Diseased Skin, abstract. SPIE BiOS'96, San Jose, CA, Jan. 27-Feb. 2, 1996, Paper 2671E-42, Session 8, p. 12.
Zeng et al., Quantative Analysis of Laser Induced Autofluorescence Spectra of Diseased Skin, abstract. Photonics China '96, Lasers in Medicine and Denistry: Diagnostics and Treatment, Beijing, China, Nov. 4-7, 1996.
Zeng et al., Reconstruction of in vivo skin autofluorescence spectrum from microscopic properties by Monte Carlo simulation. Journal of Photochemistry and Photobiology B: Biology 38: 234-240, 1997.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Fluorescence scope system for dermatologic diagnosis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Fluorescence scope system for dermatologic diagnosis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluorescence scope system for dermatologic diagnosis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-945295

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.