Compositions – Organic luminescent material containing compositions
Patent
1989-07-22
1990-08-28
Niebling, John F.
Compositions
Organic luminescent material containing compositions
C09K 1106
Patent
active
049523368
ABSTRACT:
This disclosure relates to a method and reagents for determining amphetamine and methamphetamine in a biological fluid such as urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure for determining the presence of amphetamine and methamphetamine in a single assay and to a novel class of tracer compounds employed as reagents in such procedures. The procedure described includes pretreatment of the biological sample to eliminate cross-reactants such as .beta.-hydroxyphenethylamine by preincubating the sample solely with an aqueous periodate solution having a pH from about 4.0 to about 7.5 without adjustment to an alkaline pH.
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Brynes Paul J.
Martinus Janis A.
Molina Cynthia M.
Smith Catherine M.
Vaughan Kenward S.
Abbott Laboratories
Hastreiter Roberta L.
Marquis Steven P.
Niebling John F.
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