Fluorescence polarization immunoassay for heavy antigens

Chemistry: analytical and immunological testing – Biospecific ligand binding assay

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Details

935 76, 935 81, 935 88, 436512, 436536, 436537, 436546, 436800, G01N 33566, G01N 33563, G01N 33536, G01N 33533

Patent

active

046818596

ABSTRACT:
Methods for determining the presence of large molecular weight aqueous ligands. The sample ligands are made to compete with user supplied fluorescently labeled peptides for binding sites on a ligand binding partner. Presence of aqueous ligand and binding of ligand binding partner thereto leaves the fluorescently labeled peptides free to exhibit fluorescence depolorization effects.

REFERENCES:
patent: 3939350 (1976-02-01), Kronick et al.
patent: 4420568 (1983-12-01), Wang et al.
patent: 4476228 (1984-11-01), Huchzermeier et al.

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