Chemistry: analytical and immunological testing – Biospecific ligand binding assay
Patent
1984-09-21
1987-07-21
Nucker, Christine M.
Chemistry: analytical and immunological testing
Biospecific ligand binding assay
935 76, 935 81, 935 88, 436512, 436536, 436537, 436546, 436800, G01N 33566, G01N 33563, G01N 33536, G01N 33533
Patent
active
046818596
ABSTRACT:
Methods for determining the presence of large molecular weight aqueous ligands. The sample ligands are made to compete with user supplied fluorescently labeled peptides for binding sites on a ligand binding partner. Presence of aqueous ligand and binding of ligand binding partner thereto leaves the fluorescently labeled peptides free to exhibit fluorescence depolorization effects.
REFERENCES:
patent: 3939350 (1976-02-01), Kronick et al.
patent: 4420568 (1983-12-01), Wang et al.
patent: 4476228 (1984-11-01), Huchzermeier et al.
DeSantis Patricia L.
Hofer Mark A.
Nucker Christine M.
Ortho Diagnostic Systems Inc.
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