Fluorescence polarization immunoassay

Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...

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544300, 546136, 548525, C07D22322

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active

049526910

ABSTRACT:
This disclosure relates to a method and reagents for determining ligands in biological fluids such as serum, plasma, spinal fluid, amnionic fluid and urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure and to a novel class of tracer compounds employed as reagents in such procedures. The procedure disclosed combines the specificity of an immunoassay with the speed and convenience of fluorescence polarization techniques to provide a means for determining the amount of the specific ligand present in a sample.

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patent: 4351760 (1982-09-01), Khanna et al.
patent: 4481136 (1984-11-01), Khanna et al.
patent: 4585862 (1986-04-01), Wang et al.
patent: 4588697 (1986-05-01), Khanna et al.
Morrison & Boyd; Organic Chemistry (1959), pp. 555-556, Allyn & Bacon, Inc., Boston-U.S.A.
Webster's New World Dictionary of the American Language (1972), 2nd college ed., p. 44.

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