Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides
Patent
1991-10-15
1993-08-24
Chan, Y. Christina
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Cyclic peptides
530350, 530363, 530806, 530807, C07K 764, C07K 1300, C07K 1500
Patent
active
052390578
ABSTRACT:
The present invention is directed to a fluorescence polarization immunoassay for cyclosporin A and metabolites thereof. The present invention also relates to novel cyclosporin A derivative compounds useful in fluorescence polarization techniques. Included among the novel compounds are cyclosporin A derivatives where the amino acid in the first position is altered. The cyclosporin A derivatives are useful in forming immunogens for raising antibodies specific to cyclosporin A and metabolites thereof.
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Morrison Marjorie A.
Wang Nai-Yi
Wang Philip P.
Abbott Laboratories
Breininger Thomas M.
Chan Y. Christina
Pope Lawrence S.
Steele Gregory W.
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