Fluorescence polarazation immunoassay for tetrahydrocannabinoids

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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5303898, 5303913, 5303915, 530802, 546 89, C07D44116, C09B 29033, C01K 300

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active

054630274

ABSTRACT:
This disclosure related to a method and reagents for determining tetrahydrocannabinoids (THC) and THC metabolites in a biological fluid such as urine. In particular, this disclosure relates to a fluorescence polarization immunoassay procedure for determining the presence of THC and to a novel class of tracer compounds employed as reagents in such procedures. The procedure described also provides for novel wash reagent for a THC fluorescence polarization assay.

REFERENCES:
patent: 4438207 (1984-03-01), Fahrenholtz et al.
patent: 5144030 (1992-09-01), Wang et al.
patent: 5264373 (1993-11-01), Wang et al.
Pars et al, Jol. of Medical Chem. vol. 19, No. 4 pp. 445, 545 "Drugs Derived from Cannabinoids" (1976).

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