Fluorescence imaging instrument utilizing fish

Details Fluorescence imaging instrument utilizing fish Fluorescence imaging instrument utilizing fish

1996-01-11

1999-01-26

Marschel, Ardin H.

Chemical apparatus and process disinfecting, deodorizing, preser

Analyzer, structured indicator, or manipulative laboratory...

Means for analyzing liquid or solid sample

422 50, 422 55, 422 681, 422 8205, 435 6, 4352831, 4352872, 4352871, 4352883, 4352887, 436501, 935 77, 935 78, 935 88, C12M 140, C12Q 168

Patent

active

058635041

ABSTRACT:
A method and apparatus of imaging fluorescence in situ hybridization (FISH) is provided. The instrument allows the user to simultaneously acquire images from several different colors. This system, used in conjunction with a combinatorial fluorescence approach, is able to create a FISH karyotype with each chromosome being painted with a different color. The optical system is continuously tunable over the detection wavelengths. In one embodiment of the system the sample is simultaneously irradiated in more than one wavelength band and the detection system uses a common path interferometer to scan through the detection wavelengths.

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