Fluorescence detector geometry

Optics: measuring and testing – Sample – specimen – or standard holder or support – Fluid containers

Reexamination Certificate

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C356S317000

Reexamination Certificate

active

10650213

ABSTRACT:
Excitation light of a selected wavelength from an excitation monochromator is directed along the long axis of a flow cell containing the sample to be analyzed, generating fluorescence. An emission monochromator is positioned at right angles to the plane of the excitation monochromator and receives the fluorescence from the flow cell utilizing optical components positioned such that the entrance slit of the emission monochromator is aligned with the long axis of the emission window. The intensity of the output from the flow cell is further maximized by positioning a retro-reflecting mirror at the end of the flow channel to effectively double the path-length of the excitation beam, and a reflecting surface on the side of the cell opposite the emission window to increase the collection efficiency and thereby increase the sensitivity of the detector.

REFERENCES:
patent: 3704951 (1972-12-01), Chupp
patent: 3715585 (1973-02-01), Harrick
patent: 3734601 (1973-05-01), Heiss
patent: 3807862 (1974-04-01), Hatzenbuhler
patent: 4345837 (1982-08-01), Kallet
patent: 4394237 (1983-07-01), Donnelly
patent: 4988195 (1991-01-01), Doyle
patent: 5194915 (1993-03-01), Gilby
patent: 5327225 (1994-07-01), Bender
patent: 5329353 (1994-07-01), Ischimura
patent: 5444807 (1995-08-01), Liu
patent: 5452723 (1995-09-01), Wu
patent: 5780857 (1998-07-01), Harju et al.
patent: 5917606 (1999-06-01), Kaltenbach
patent: 6046807 (2000-04-01), Chandler
patent: 6795177 (2004-09-01), Doyle
patent: 2002/0171827 (2002-11-01), van den Engh
patent: 2003/0202175 (2003-10-01), van den Engh et al.
patent: 2005/0012929 (2005-01-01), Booker et al.
patent: 46-009915 (1971-07-01), None
patent: 64-091037 (1989-04-01), None
patent: 7-500191 (1995-05-01), None
patent: 08-159971 (1996-06-01), None
patent: 09-184808 (1997-07-01), None
patent: 10-221244 (1998-08-01), None
R. Altkorn, et al.; “Low-loss liquid-core optical fiber for low-refractive-index liquids; fabrication, characterization . . . ”, Applied Optics/vol. 36, No. 34/Dec. 1, 1997.
Fujiwata, et al.; Side-View Type of Waveguide Flow Cells for Fluorimetry as a Detector for Flow Injection Analysis of Lead, Applied Spectroscopy, vol. 46, No. 6, 1992.
Walrafen, et al.; Intensification of Spontaneous Raman Spectra by Use of Liquid Core Optical Fibers, Applied Spectroscopy, vol. 26, No. 6, 1972.

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