Fluorescence detection type electrophoresis apparatus

Details Fluorescence detection type electrophoresis apparatus Fluorescence detection type electrophoresis apparatus

1991-04-12

1994-04-26

Rosenberger, Richard A.

Optics: measuring and testing

By electrophoresis

356417, G01N 2164

Patent

active

053071484

ABSTRACT:
A multicolor fluorescence detection type electrophoresis apparatus comprises an electrophoretic device having migration lanes in which fragment groups specifically labeled by fluorophores of different light emission peak wavelengths are mixed, added, and migrated. It identifies and detects the fragment groups. It uses laser beams of different wavelengths for exciting the fluorophores in the migration lanes. The laser beams are irradiated to separate positions on the migration lanes for detection of a few kinds of fluorophores at irradiation positions. For the purpose, multicolor optical filters are arranged near the irradiation positions to identify and detect lights emitted from the fluorophores excited by wavelength at every irradiation position.

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patent: 4881812 (1989-11-01), Ohkubo et al.
patent: 5062942 (1991-11-01), Kambara et al.
"Science", vol. 238, pp. 336-341 (Oct. 16, 1987).
"Nature", vol. 321, pp. 674-679 (Jun. 12, 1986).

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