Fluorescence based biosensor

Details Fluorescence based biosensor Fluorescence based biosensor

2005-05-10

2005-05-10

Sisson, Bradley L. (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091100, C435S287200, C436S094000, C436S800000, C536S023100

Reexamination Certificate

active

06890719

ABSTRACT:
A novel biosensor comprises at least one fluorophore and at least two quenchers, and is capable of selectively and specifically detecting the presence of an ion in the presence of other ions.

REFERENCES:
patent: 6451535 (2002-09-01), Jenne et al.
patent: 19915141 (2000-09-01), None
patent: WO 9947704 (1999-09-01), None
patent: WO 0200006 (2002-01-01), None
Merriam-Webster OnLine; definition of “ion,” accessed and printed Mar. 7, 2004.*
Jenne, A.; Gmelin, W.; Raffler, N.; Famulok, M. Real-time Characterization of Ribozymes by Fluorescence Resonance Energy Transfer (FRET).Angewandte Chemie, International Edition, Verlag Chemie.May 3, 1999, vol. 38, No. 9, 1300-1303.*
Jenne, A.; Hartig, J. S.; Piganeau, N.; Tauer, A.; Samarsky, D. A.; Green, M. R.; Davies, J.; Famoluk, F. Rapid Identification and Characterization of Hammerhead-Ribozyme Inhibitors Using Fluorescence-Based Technology.Nature Biotechnology.Jan. 1, 2002, vol. 19, No. 1, 56-61.*
Singh, K. K.; Rucker, T.; Hanne, A.; Parwaresch, R.; Krupp, G. Fluorescence Polarization for Monitoring Ribozyme Reactions in Real-Time.Biotechniques.Aug. 2000, vol. 29, No. 2, 344-351.*
Bogden, J.D.; Louria, D.B.Bull. Environ. Contam. Toxicol.1975, 14:289-94.
Breaker, R. R.; Joyce, G. F.Chem. Biol.1995, 2, 655-660.
Breaker, R.R. & Joyce, G.F. A DNA enzyme that cleaves RNA.Chem. Biol.1, 223-229 (1994).
Breaker, R.R. DNA enzymes.Nat. Biotechnol.15, 427-431 (1997).
Cadwell, R. C.; Joyce, G. F.PCR Methods Appl.1992, 2, 28-33.
Cadwell, R. C.; Joyce, G. F.PCR Methods Appl.1994, 3, S136-S140.
Carmi, N., Shultz, L.A. & Breaker, R.R. In vitro selection of self-cleaving DNAs.Chem. Biol.3, 1039-1046 (1996).
Chapman, K. B.; Szostak, J. W.Curr. Opin. Struct. Biol.1994, 4, 618-622.
Ciesiolka, J.; Gorski, J.; Yarus, M.RNA1995, 1, 538-550.
Ciesiolka, J.; Yarus, M.RNA1996, 2, 785-793.
Conaty, J.; Hendry, P.; Lockett, T.Nucleic Acids Res.1999, 27, 2400-2407.
Conn, M. M.; Prudent, J. R.; Schultz, P. G.J. Am. Chem. Soc.1996, 118, 7012-7013.
Cuenoud, B. & Szostak, J.W. A DNA metalloenzyme with DNA ligase activity.Nature375, 611-614 (1995).
Czarnik, A.W. Desperately seeking sensors.Chem. Biol.2, 423-428 (1995).
Dai, X.; De Mesmaeker, A.; Joyce, G. F.Science1995, 267, 237-240.
Deo, S. & Godwin, H.A. A Selective, Ratiometric Fluorescent Sensor for Pb2+.J. Am. Chem. Soc.122, 174-175 (2000).
Didenko, V.V.,BioTechniques2001, 31:1106-18.
Earnshaw & Gait, “Modified Oligoribonucleotides as site-specific probes of RNA structure and function,”Biopolymers(John Wiley & Sons, Inc.) 48:39-55, 1998.
Ekland, E. H.; Szostak, J. W.; Bartel, D. P.Science1995, 269, 364-370.
Ekland, E. H.; Bartel, D. P.Nature1996, 382, 373-376.
Famulok, M.Curr. Opin Struct. Biol.1999, 9, 324-329.
Faulhammer, D.; Famulok, M.Angew. Chem., Int. Ed. Engl.1997, 35, 2837-2841.
Fodor, S.P.A., Read, J.L., Pirrung, M.C., Stryer, L., Lu, A.T. & Solas, D. (1991). Light-directed, spatially addressable parallel chemical synthesis.Science251: 767-773.
Frank, D. N.; Pace, N. R.Proc. Natl. Acad. Sci. U. S. A.1997, 94, 14355-14360.
Geyer, C. R.; Sen, D.Chem. Biol.1997, 4, 579-593.
Godwin, H.A. & Berg, J.M. A Fluorescent Zinc Probe Based on Metal-Induced Peptide Folding.J. Am. Chem. Soc.118, 6514-6515 (1996).
Guschin, D., Yershov, G., Zaslavsky, A., Gemmell, A., Shick, V., Proudnikov, D., Arenkov, P. & Mirzabekov, A. (1997). Manual manufacturing of oligonucleotide, DNA, and protein microchips.Anal. Biochem.250: 203-211.
Hennrich, G.; Sonnenschein, H.; Resch-Genger, U.J. Am. Chem. Soc.1999, 121, 5073-5074.
Illangasekare, M.; Yarus, M.J. Mol. Biol.1997, 268, 631-639.
Imperiali, B., Pearce, D.A., Sohna, J.-E., Walkup, G. & Torrado, A. Peptide platforms for metal ion sensing.Proc. SPIE-Int. Soc. Opt. Eng.3858, 135-143 (1999).
Jhaveri, et al., Designed Signaling Aptamers that Transduce Molecular Recognition to Changes in Fluorescence Intensity,Journal of the American Chemical Society;2000; 122(11); 2469-2473.
Joos, B., Kuster, H. & Cone, R. (1997). Covalent attachment of hybridizable oligonucleotides to glass supports.Anal. Biochem.247: 96-101.
Joyce, G. F.Curr. Opin. Struct. Biol.1994, 4, 331-336.
Koizumi, M.; Soukup, G. A.; Kerr, J. N. Q.; Breaker, R. R.Nat. Struct. Biol.1999, 6, 1062-1071.
Lee, M., & Walt, D. R. A fiber-optic microarray biosensor using aptamers as receptors.Anal Biochem282(1):142-146, 2000.
Lehman, N.; Joyce, G.F.Nature1993, 361, 182-185.
Li, J., Zheng, W., Kwon, A.H. & Lu, Y. In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme.Nucleic Acids Res.28, 481-488 (2000).
Li, Y.; Sen, D.Nat. Struct. Biol.1996, 3, 743-747.
Li, Y.; Breaker, R. R.Proc. Natl. Acad. Sci. U. S. A.1999, 96, 2746-2751.
Li, Y.; Liu, Y.; Breaker, R. R.Biochemistry2000, 39, 3106-3114.
Lohse, P.A.; Szostak, J. W.Nature1996, 381, 442-444.
Lorsch, J. R.; Szostak, J. W.Nature1994, 371, 31-36.
Marcus, A.H.; Elias, R.W.ASTM Spec. Tech. Publ.1995,STP 1226:12-23.
Miyawaki, A., et al. Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin.Nature388, 882-887 (1997).
O'Donnel-Maloney, M.J., Tang, K., Koester, H., Smith, C.L. & Cantor, C.R. (1997). High-Density, Covalent Attachment of DNA to Silicon Wafers for Analysis by MALDI-TOF Mass Spectrometry.Anal. Chem.69:2438-2443.
Oehme, I. & Wolfbeis, O.S. Optical sensors for determination of heavy metal ions.Mikrochim. Acta126, 177-192 (1997).
Pan, T. & Uhlenbeck, O.C. A small metalloribozyme with a two-step mechanism.Nature358, 560-563 (1992).
Pan, T.; Dichtl, B.; Uhlenbeck, O. C.Biochemistry1994, 33, 9561-9565.
Pearce, D. A.; Walkup, G. K.; Imperiali, B.Bioorg. Med. Chem. Lett.1998, 8, 1963-1968.
Pease, A.C., Solas, D., Sullivan, E.J., Cronin, M.T., Holmes, C.P. & Fodor, S.P.A. (1994). Light-generated oligonucleotide arrays for rapid DNA sequence analysis.Proc. Natl. Acad. Sci. U. S. A.91: 5022-5026.
Piccirilli, J. A.; McConnell, T. S.; Zaug, A. J.; Noller, H. F.; Cech, T. R.Science1992, 256, 1420-1424.
Pley, H. W.; Flaherty, K. M.; McKay, D. B.Nature1994, 372, 68-74.
Potyrailo, R.A., Conrad, R.C., Ellington, A.D. & Hieftje, G.M. (1999). Adapting Selected Nucleic Acid Ligands (Aptamers) to Biosensors.Anal. Chem.70: 3419-3425.
Prudent, J. R.; Uno, T.; Schultz, P. G.Science1994, 264, 1924-1927.
Rabinowitz, M.; Leviton, A.; Bellinger, D.Am. Jour. Public Health Field.1985, Apr. 75: 403-4.
Robertson, M. P.; Ellington, A. D.Nat. Biotechnol.1999, 17, 62-66.
Robertson, M. P.; Ellington, A. D.Nucleic Acids Res.2000, 28, 1751-1759.
Roth, A.; Breaker, R. R.Proc. Natl. Acad. Sci. U. S. A.1998, 95, 6027-6031.
Rurack, K., Kollmannsberger, M., Resch-Genger, U. & Daub, J. A Selective and Sensitive Fluoroionophore for HgII, AgI, and CuII with Virtually Decoupled Fluorophore and Receptor Units.J. Am. Chem. Soc.122, 968-969 (2000).
Santoro, S. W.; Joyce, G. F.Proc. Natl. Acad. Sci. U. S. A.1997, 94, 4262-4266.
Santoro, S.W., Joyce, G.F., Sakthivel, K., Gramatikova, S. & Barbas, C.F., III RNA Cleavage by a DNA Enzyme with Extended Chemical Functionality.J. Am. Chem. Soc.122, 2433-2439 (2000).
Schwartz, J.; Levin, R.Env. Research Field.1991, Feb. 54: 1-7.
Scott, W. G.; Finch, J. T.; Klug, A.Cell1995, 81, 991-1002.
Tang and Breaker,Proc. Natl. Acad. Sci. USA,97, 5784-5789 (2000).
Tarasow, T. M.; Tarasow, S. L.; Eaton, B. E.Nature1997, 389, 54-57.
Thompson, R.B., Maliwal, B.P., Feliccia, V.L., Fierke, C.A. & McCall, K. Determination of Picomolar Concentrations of Metal Ions Using Fluorescence Anisotropy: Biosensing with a “Reagentless” Enzyme Transducer.Anal. Chem.70, 4717-4723 (1998).
Tsang, J.; Joyce, G. F.Methods Enzymol.1996, 267, 410-426.
Tsien, R.Y. Fluorescent and photochemical probes of dynamic biochemical signals inside living cells. inFluorescent Chemosensors for Ion and Molecule Recognization(ed. Czarnik, A.W.) 130-46 (American Chemical Society, Washington, DC, 1993).
Tuerk, C.; Gold, L.Science1990, 249, 505-510.
Tyagi S; Kramer, F.R.Nat. Biotechnol.1996 14, 303-308.
Tyagi, S.; Bratu, D.P.;

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