Fluoralkylatedcarbapenem derivatives

Details Fluoralkylatedcarbapenem derivatives Fluoralkylatedcarbapenem derivatives

1985-10-30

1988-01-19

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540350, C07D48704, A61K 3140

Patent

active

047204907

ABSTRACT:
6-(1'-fluorethyl)- and 6-(1'-fluoro-1'-methylethyl)-carbapenems such as (5RS,6RS)-1-aza-6-(1(RS)-fluorethyl)-3-(N'-dimethyl-N'-methylamidinomethyl thio)-7-oxobicyclo[3.2.0]hept-2-ene-2-carboxylic acid which are useful as chemotherapeutic agents in particular as anti-bacterially active anti-biotics.

REFERENCES:
patent: 4372965 (1983-02-01), Christensen et al.
patent: 4413000 (1983-11-01), Eglington
patent: 4477662 (1984-10-01), Corbett et al.
Mak, (Amer. Med. Chem. Symposium), Toronto, Canada, Jun. 1982.

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