Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Digestive system
Patent
1994-11-22
1996-05-14
Knode, Marian C.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
Digestive system
623 14, A61K 3538
Patent
active
055165338
ABSTRACT:
A fluidized, injectable tissue graft composition is described. The composition comprises comminuted intestinal submucosa or protease-digested intestinal submucosa. Methods for the preparation and use of injectable tissue graft compositions are described. In preferred embodiments the tissue graft material is prepared from the intestinal submucosa comprising the tunica submucosa, the muscularis mucosa and the stratum compactum of a segment of intestinal tissue of a warm-blooded vertebrate. Effective amounts of the fluidized graft compositions can be injected to promote repair tissue defects by inducing formation of endogenous tissues.
REFERENCES:
patent: 4902508 (1990-02-01), Badylak et al.
patent: 4956178 (1990-09-01), Badylak et al.
"Polytef Augmentation Urethroplasty", Solomon Berg, Arch. Surg. vol. 107, Sep. 1973, pp. 379-381.
"Teflon Injection in Stress Incontinence", A. M. Deane, et al., British Journal of Urology, (1985), 57, 78-80.
"Periurethral Teflon Injection: A Simple Treatment For Urinary Incontinence", K. B. Lim , et al, British Journal of Urology, (1983), 55, 208-210.
"Periurethal Teflon Injection For Urinary Incontinence", Victor A. Politano, et al., The Journal of Urology, Feb. 1974, pp. 180-183.
"Treatment of Urinary Incontinence by the Periurethral Implantationof Glutaraldehyde Cross-Linked Collagen", Linda M. D. Shortliffe, et al., The Journal of Urology, vol. 141, Mar. 1989, pp. 538-541.
"Why We've Abandoned Polytef Injection For VUR", Mark. Burns et al., Contemporary Urology, Dec. 1991, pp. 40-43.
"Replacement of Dog's Aorta by Autologous Intestinal Muscle in the Infected Retroperitoneum", R. Broll, et al., Eurp. Surg. Res., 18: 390-396 (1986).
"Comparison of Bovine Collagen Xenografts to Autografts in the Rabbit", J. C. Tauro, et al., Clinical Orthopaedics and Related Research, No. 266, May, 1991, pp. 271-284.
"Development of a Reconstituted Collagen Tendon Prosthesis", Jack D. Goldstein, et al., The Journal of Bone and Joint Surgery, Incorporated, vol. 71-A, No. 8, Sep. 1989, pp. 1183-1191.
"Aortic Replacement with Multi-Layer Submucosa Prostheses Made From Heterologous Small Intestine", G. Rotthoff, et al., presented at 8th Congress of the International Society of Cardiovascular Surgery, Vienna, Sep. 7-9, 1967.
"Replacement of the Abdominal Aorta by an Ileum Muscle Tube in an Animal Experiment", J. Huth, et al., (translation), Thoraxchir. Vask, Chir., 15(4): 401-407, Aug. 1967.
"Long Term Observations and Histological Studies on Vessel and Heart Wall Grafts From Small Intestine", R. Haring, et al., Langenbecks Arch. Klin. Chir., 1965, 313:664-8.
"Replacement of the Abdominal Aorta With A Small-Intestine Muscle Tube In An Animal Experiment", J. Huth, Zentralbl Chir., 92 (26/2): 1817-19 (1967).
"Reconstruction of the Arterial Flow Path by Autologous Intestinal Muscle Grafts in The Dog", H. P. Bruch, et al., Folia Angiologica, vol. 29 (3-5/81) pp. 65-68.
"Replacement of the Aorta by Multilayered Submucosa Prostheses of Heterologous Ileum", G. Rotthoff, et al., Bulletin de la Societe International de Chirurgie, No. 2, 1969, 256-259.
Badylak Stephen F.
Demeter Robert J.
Hiles Michael
Knapp, Jr. Peter M.
Voytik Sherry
Knode Marian C.
Methodist Hospital of Indiana Inc.
Purdue Research Foundation
Witz Jean C.
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