Fluidized bed separation and recovery of proteins from fluids in

Details Fluidized bed separation and recovery of proteins from fluids in Fluidized bed separation and recovery of proteins from fluids in

1991-01-22

1992-02-11

Therkorn, Ernest G.

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210657, 2101982, 426491, 530395, 530413, 530417, B01D 1508

Patent

active

050873695

ABSTRACT:
Disclosed is a method for separating and recovering very small amounts of biologically active proteins (such as enzymes, antigens and antibodies) present in a various fluids, with a high recovery and on a large scale, in which a fluid containing a desired protein is introduced into a rotary column through orifices therein and brought into contact with a gel carrier capable of selectively adsorbing the desired protein, while the carrier is being gentle fluidized in a liquid by the rotary motion successively by wash water and eluting fluid, so that the column, after which the fluid is displaced, the carrier having the desired protein adsorbed thereon is washed and the desired protein is recovered therefrom by elution while the carrier fluidized.

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