Agitating – Stationary mixing chamber
Reexamination Certificate
2005-08-30
2005-08-30
Walker, W. L. (Department: 1723)
Agitating
Stationary mixing chamber
C137S833000, C137S827000, C137S550000, C422S105000, C422S105000
Reexamination Certificate
active
06935772
ABSTRACT:
Microfluidic devices capable of efficiently mixing two or more fluid are provided. Two or more microfluidic inlet channels defined in different sheets of material meet at an overlap region in fluid communication with an outlet channel. The channels are defined through the entire thickness of stencil sheets. The overlap region may include an aperture-defining spacer layer, and/or an impedance element, such as a porous membrane, adapted to distribute at least one fluid across the entire width of the outlet channel to promote reliable fluid mixing.
REFERENCES:
patent: 4946795 (1990-08-01), Gibbons et al.
patent: 5070606 (1991-12-01), Hoopman et al.
patent: 5194133 (1993-03-01), Clark et al.
patent: 5222808 (1993-06-01), Sugarman et al.
patent: 5230866 (1993-07-01), Shartle et al.
patent: 5376252 (1994-12-01), Ekstrom et al.
patent: 5385709 (1995-01-01), Wise et al.
patent: 5443890 (1995-08-01), Ohman
patent: 5534328 (1996-07-01), Ashmead et al.
patent: 5545367 (1996-08-01), Bae et al.
patent: 5595712 (1997-01-01), Harbster et al.
patent: 5640995 (1997-06-01), Packard et al.
patent: 5646039 (1997-07-01), Northrup et al.
patent: 5658515 (1997-08-01), Lee et al.
patent: 5690763 (1997-11-01), Ashmead et al.
patent: 5698299 (1997-12-01), Schmidt et al.
patent: 5771810 (1998-06-01), Wolcott
patent: 5842787 (1998-12-01), Kopf-Sill et al.
patent: 5849208 (1998-12-01), Hayes et al.
patent: 5858188 (1999-01-01), Soane et al.
patent: 5869004 (1999-02-01), Parce et al.
patent: 5872010 (1999-02-01), Karger et al.
patent: 5882465 (1999-03-01), McReynolds
patent: 5882571 (1999-03-01), Kaltenbach et al.
patent: 5904424 (1999-05-01), Schwesinger et al.
patent: 5904824 (1999-05-01), Oh
patent: 5921678 (1999-07-01), Desai et al.
patent: 5922591 (1999-07-01), Anderson et al.
patent: 5932315 (1999-08-01), Lum et al.
patent: 5932799 (1999-08-01), Moles
patent: 5945203 (1999-08-01), Soane
patent: 6004515 (1999-12-01), Parce et al.
patent: 6007775 (1999-12-01), Yager
patent: 6030581 (2000-02-01), Virtanen
patent: 6074725 (2000-06-01), Kennedy
patent: 6136272 (2000-10-01), Weigl et al.
patent: 6186660 (2001-02-01), Kopf-Sill et al.
patent: 6190034 (2001-02-01), Nielsen et al.
patent: 6193471 (2001-02-01), Paul
patent: 6235471 (2001-05-01), Knapp et al.
patent: 6264900 (2001-07-01), Schubert et al.
patent: 6287520 (2001-09-01), Parce et al.
patent: 6296020 (2001-10-01), McNeely et al.
patent: 6409832 (2002-06-01), Weigl et al.
patent: 6418968 (2002-07-01), Pezzuto et al.
patent: 6482306 (2002-11-01), Yager et al.
patent: 6494614 (2002-12-01), Bennett et al.
patent: 6537506 (2003-03-01), Schwalbe et al.
patent: 2001/0048637 (2001-12-01), Weigl et al.
patent: 2001/0048900 (2001-12-01), Bardell et al.
patent: 2002/0048535 (2002-04-01), Weigl et al.
patent: 2002/0076350 (2002-06-01), Weigl et al.
patent: 2002/0187074 (2002-12-01), O'Connor et al.
patent: 2002/0192701 (2002-12-01), Adey
patent: 2003/0123322 (2003-07-01), Chung et al.
patent: 0 107 631 (1984-05-01), None
patent: 0 933 126 (1999-08-01), None
patent: 1 123 734 (2001-08-01), None
patent: WO 97/00125 (1997-01-01), None
patent: WO 97/12665 (1997-04-01), None
patent: WO 98/45693 (1998-10-01), None
patent: WO 98/56505 (1998-12-01), None
patent: WO 99/17093 (1999-04-01), None
patent: WO 99/19717 (1999-04-01), None
patent: WO 99/29497 (1999-06-01), None
patent: WO 99/60397 (1999-11-01), None
patent: WO 00/21659 (2000-04-01), None
patent: WO 00/22436 (2000-04-01), None
patent: WO 01/28670 (2001-04-01), None
patent: WO 02/10732 (2002-02-01), None
Groisman et al.,Microfluidic Memory and Control Devices,“Science Magazine,” vol. 300, May 9, 2003, pp. 955-958.
Stroock, Abraham D., et al.,Chaotic Mixer for Microchannels,“Science Magazine,” vol. 295, Jan. 25, 2002, The American Association for the Advancement of Science, Stanford University's HighWire Press, pp. 647-651.
Jacoby, Mitch,Chemistry Flows Like Clockwork—Flow system used to make simple devices for time-dependent studies,“Chemical & Engineering News,” Feb. 24, 2003, p. 5.
Deshmukh, Ajay A., et al., A.P. (2000), “Continuous Micromixer with Pulsatile Micropumps,” Solid-State Sensor and Actuator Workshop, Hilton Head Island, SC, USA, Jun. 4-8, 2000, pp. 73-76.
Martin, P.M., et al.,Laser micromachined and laminated microchannel components for chemical sensors and heat transfer applications,“Micromachined Devices and Components III,” SPIE—The International Society for Optical Engineering, vol. 3224, Bellingham, Washington, USA, pp. 258-265.
Tracey, M.C., et al., “Microfluidic Mixer Employing Temporally-Interleaved Liquid Slugs and Parabolic Flow,”Micro Total Analysis Systems,J.M. Ramsey and A. van den Berg (eds.), 2001 Kluwer Academic Publishers, Netherlands, pp. 141-142.
Ehrfeld, Wolfgang, et al., “Injection of Many Small Substreams of One Component into a Main Stream of Another Component,”Microreactors—New Technology for Modern Chemistry,Vch Verlagsgesellschaft Mbh; 1stedition, Jun. 15, 2000, pp. 53-55.
Liu, Robin H., et al., “Plastic In-Line Chaotic Micromixer for Biological Application,”Micro Total Analysis Systems,J.M. Ramsey and A. van den Berg (eds.), 2001 Kluwer Academic Publishers, Netherlands, pp. 163-164.
Ehrfeld, W., et al.,Potentials and Realization of Microreactors,“DECHEMA Monographs,” vol. 132, VCH Verlagsgesellschaft, 1996, pp. 1-28.
Johnson, Timothy J., et al.,Rapid Microfluidic Mixing,“Analytical Chemistry,” vol. 74, No. 1., Jan. 1, 2002, pp. 45-51.
Verpoorte, Elisabeth M. J., et al., “Silicon-Based Chemical Microsensors and Microsystems,”Interfacial Design and Chemical Sensing,American Chemical Society 1994, Chapter 21, pp. 244-254.
Bertsch, Arnaud, et al.,Static micromixers based on large-scale industrial mixer geometry,“Lab on a Chip,” The Royal Society of Chemistry, 2001, 1, pp. 56-60.
Branebjerg, Jens, et al., “Fast Mixing by Lamination,” Proc. Micro Electro Mechanical Systems Workshop, pp. 441-446, IEEE (1996).
Miyake, Ryo, et al., “Micro Mixer with Fast Diffusion,” Proc. Micro Electro Mechanical Systems Workshop, pp. 248-253, IEEE (1993).
Mensinger, H., et al., “Microreactor With Integrated Static Mixer and Analysis System,” Micro Total Analysis Systems, pp. 237-240, Kluwer, The Netherlands (1995).
Larsen, Ulrik D., et al.. “Fast Mixing by Parallel Multilayer Lamination,” Analytical Methods & Instrumentation, Proc. 2ndInternational Symposium Miniaturized Total Analysis Systems μTAS-96, pp. 228-230 (1996).
Merkel, Tobias, et al., “A New Technology for Fluidic Microsystems Based on PCB Technology,” Sensors and Actuators 77 A:Physical, pp. 98-105, 1999.
Knight, James B., et al., “Hydrodynamic Focusing on a Silicon Chip: Mixing Nanoliters in Microseconds,” Physical Review Letters, vol. 80, No. 17, Apr. 27, 1998.
Bökenkamp, Dirk , et al., “Microfabricated Silicon Mixers for Submillisecond Quench-Flow Analysis,” Anal. Chem. 70, pp. 232-236, 1998.
Svasek,P., et al., “Dry Film Resist Based Fluid Handling Components for μTAS” Institute für Allgemeine Elektrotechnik und Elektronik, Technische Universität Wien, undated.
Shoji, Shuichi, “Fluids for Sensor Systems,” Topics in Current Chemistry, vol. 194, 1998.
McNeely, Michael R., et al., “Hydrophobic Microfluidics,” SPIE Microfluidic Devices & Systems II, vol. 3877, Sep. 1999.
Desai, Amish et al., “Microfluidic Sub-millisecond Mixers For The Study of Chemical Reaction Kinetics,” Transducers 97 (1997 Int'l Conf. on Solid-State Sensors and Actuators), vol. 1, pp. 167-170, Jun. 16-19, 1997.
Weigl, Bernhard H., et al., “Passive Microfluidics-Ultra-low-cost plastic disposable lab-on-a-chip,” μ-TAS 2000, Twente, the Netherlands, May 14-18, 2000.
Ehrfeld, Wolfgang et al., “Characterization of Mixing in Micromixers by a Test Reaction: Single Mix
Karp Christoph D.
O'Connor Stephen D.
Patel Paren P.
Gustafson Vincent K.
Menon Krishnan S
Nanostream, Inc.
Walker W. L.
LandOfFree
Fluidic mixer in microfluidic system does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Fluidic mixer in microfluidic system, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Fluidic mixer in microfluidic system will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3518807