Fluid vessel

Special receptacle or package – For mixing – Tear strip or piercer

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Details

206219, B65D 2508

Patent

active

058267131

DESCRIPTION:

BRIEF SUMMARY
This is a continuation of application Ser. No. PCT/JP95/02215, filed under 35 U.S.C. .sctn. 371.


TECHNICAL FIELD OF THE INVENTION

The present invention relates to a fluid vessel and, more particularly, to a fluid vessel for holding a dried drug such as a powder drug or a freeze-dried drug and its solvent in a separate state, and for mixing the dry drug and the solvent in the vessel in a sterile manner just before the use to supply the mixture as a solution for infusion.


BACKGROUND OF THE INVENTION

Hitherto, a dried drug contained in a drug vessel such as a vial has been dissolved in solvent such as purified water, physiological saline solution, or glucose solution for drip injection at a medical organization such as a hospital.
For simple and convenient use in these cases, there has been proposed a fluid vessel in which a vial containing a dried drug is connected in series to a solvent vessel containing solvent, whereby the two vessels are communicated in a sterile manner at the time of using (for example, Japanese Laid-open PCT Publication No. Sho 61(1986)-501129, Japanese Laid-open Patent Publication No. Hei 2(1990)-1277, and Japanese Laid-open Utility Model Publication No. Sho 63(1988)-135642).
The one disclosed in Japanese Laid-open PCT Publication No. Sho 61(1986)-501129 is a device in which a capsule having a drug vessel and a solvent vessel containing solvent are connected by a tube, whereby the drug vessel and the solvent vessel are communicated by means of a communication means provided in the tube so as to mix the drug and the solvent in a sterile manner. The one disclosed in Japanese Laid-open Patent Publication No. Hei 2(1990)-1277 is a fluid vessel as shown in FIG. 21, in which a hollow puncturing needle 117 having a hub in the middle and having knife-edges at both ends is interposed between a drug vessel 112 and a solvent vessel 111 containing solvent, and which is constructed in such a manner that the puncturing needle 117 first pierces the drug vessel 112 and then pierces the solvent vessel 111, whereby the communication between the drug vessel 112 and the solvent vessel 111 can be secured and facilitated and the mixing of the drug and the solvent after the start of communication can be carried out in a short time and in a sterile manner.
The one shown in Japanese Laid-open Utility Model Publication No. Sho 63(1988)-135642 is a device in which a tubular, suitably detachable support ring is provided at a sealing portion of a mouth portion of a solvent vessel and in which a double-edged needle is mounted onto the support ring so that the needle is slidable upwards and downwards, whereby the lower needle pierces the sealing portion of the mouth portion of the solvent vessel when the double-edged needle is allowed to slide downwards.
With respect to these fluid vessels, there has been a problem that, since the drug vessel and the solvent vessel are basically connected in a partitioned state and also it is necessary to provide, at the connecting portion, a means for mixing the drug and the solvent in the two vessels at the time of use, the total length of the fluid vessel (the length along the connecting direction) is unnecessarily long, the transportation cost is higher and it is difficult to secure the storage space. Also, in the hospitals, there is an inconvenience that a hanger must be held high in order to obtain a sufficient height difference for natural dripping. Of course, these fluid vessels are all integrated bodies incorporating therein a vial as it is, which is a typical form of distributing a dried drug and, in that sense, these vessels have a high applicability for wide uses.
However, these conventional fluid vessels, for example, the one disclosed in Japanese Laid-open PCT Publication No. Sho 61(1986)-501129, has a drawback that it has a lot of components and it takes time to bend the breaking member by hands to open a passage and, moreover, when the bending of the breaking member is incomplete, the solution is hard to pass and it takes too much time to carry out the dissolu

REFERENCES:
patent: 4936841 (1990-06-01), Aoki et al.
patent: 5170888 (1992-12-01), Goncalves
patent: 5261902 (1993-11-01), Okada et al.
patent: 5308347 (1994-05-01), Sunago et al.
patent: 5352191 (1994-10-01), Sunago et al.

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