Surgery – Container for blood or body treating material – or means used... – Materials mixed within container
Patent
1997-08-13
2000-02-01
McDermott, Corrine
Surgery
Container for blood or body treating material, or means used...
Materials mixed within container
604403, 220260, 220265, A61B 1900
Patent
active
060197528
DESCRIPTION:
BRIEF SUMMARY
TECHNICAL FIELD
The present invention relates to a fluid vessel and, more particularly, to a fluid vessel for preserving a dried drug such as a formulation in the form of powders or a freeze-dried formulation and its solvent in a separate state, and for mixing the dried drug and the solvent in the vessel in a sterile manner just before the use to supply the mixture as a solution for infusion.
BACKGROUND ART
Hitherto, a dried drug contained in a drug vessel such as a vial has been dissolved into a solvent such as distilled water, physiological saline solution, or glucose solution for drip infusion at a medical organization such as a hospital.
For simple and convenient use in such a case, there has been proposed a fluid vessel in which a vial containing a dried drug is connected in series to a solvent vessel containing a solvent, whereby the two vessels are brought into communication in a sterile manner at the time of using.
For example, a fluid vessel 410 disclosed in Japanese Laid-open Patent Publication No. Hei 2(1990 )-1277 is constructed in such a manner that, as shown in FIG. 35, a hollow puncture needle 417 having a hub in the middle and having knife-edges at both ends is interposed between a drug vessel 412 and a solvent vessel 411 containing a solvent, and the puncture needle 417 first pierces the drug vessel 412 and then pierces the solvent vessel 411, whereby the communication between the drug vessel 412 and the solvent vessel 411 can be secured and facilitated and the mixing of the drug and the solvent after the start of communication can be carried out in a short time and in a sterile manner.
The drug vessel 412 is usually sealed with a rubber plug capable of being pierced with the puncture needle 417 and having a self-sealing property. The drug vessel 412 is usually a vial made of glass which is a generally distributed form for dried drugs. The rubber plug is tightly surrounded by a covering member 413 made of aluminum or the like and is fixed onto the mouth portion of the vessel.
Also, there has been proposed a flexible duplex vessel as shown in FIG. 36, in which a plurality of chambers for storing a liquid agent, a powder agent or a solid agent are partitioned with partition means capable of communication (See Japanese Laid-open Patent Publication No. Hei 4 (1992)-364850). This vessel 510 is composed of a plurality of chambers made of flexible sheet, which include a drug solution storing chamber 501, a storing chamber 506 covered with an outer wall 502 and storing a deoxidant 504 and a desiccant 505, and a drug storing chamber 503 covered with an inner wall 508 and storing a drug. These chambers are connected via a weak sealing section 507. The vessel is constructed in such a manner that, at the time of use, the weak sealing section 507 can be easily separated by applying an outer pressure to the drug solution storing chamber 501. This facilitates the communication between the drug solution storing chamber 501 and the drug storing chamber 503. This also facilitates the disposing process of the vessels.
The former fluid vessel 410 has a high applicability and excellent operability because the vessel-uses and incorporates a vial. However, since the vial is made of glass and aluminum, it is difficult to remove and classify the components in disposing the fluid vessels separately after use. Moreover, the components such as the puncture needle 417 and other communication means between the drug vessel 412 and the solvent vessel 411 are complicated and the total number of components is large.
The latter fluid vessel 510 has a drawback that the manufacturing process is complicated since the vessel is formed by sealing a plurality of films. Moreover, since the entire vessel is formed of flexible sheets, the vessel cannot stand by itself and takes a lot of space for storage.
The above-mentioned vessels are usually used for drip infusion, as shown in FIG. 34, by allowing a liquid delivery portion 560 at the bottom of the fluid vessel 550 to be connected to a separate drip infusion device 570 includi
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Futagawa Hitoshi
Kagayama Akira
Kubo Tomohiko
Murakami Mitsuo
Sunago Seizo
Fujisawa Pharmaceutical Co. Ltd.
McDermott Corrine
Nissho Corporation
Noggle William
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