Chemistry: analytical and immunological testing – Automated chemical analysis – With aspirator of claimed structure
Patent
1994-12-16
1996-08-27
Snay, Jeffrey R.
Chemistry: analytical and immunological testing
Automated chemical analysis
With aspirator of claimed structure
436180, 422100, 422106, 73304C, 7386401, B01L 302
Patent
active
055500595
ABSTRACT:
A fluid sensing pipette includes an outer conductive tube forming a first electrode and an inner conductive tube forming a second electrode. The inner conductive tube is disposed concentrically within the outer conductive tube. To insulate the inner conductive tube from the outer conductive tube, the inner conductive tube is coated with a thin, uniform, and consistent Parylene coating. A hydrophobic polymeric tube is disposed concentrically within the inner conductive tube to prevent cross-contamination between different biological samples aspirated into the pipette. The inner and outer conductive tubes are separately coupled to a level detection circuit which permits the pipette to detect entry of the pipette into a conductive fluid. The level detection circuit determines the impedance between the first and second electrodes and produces a control signal in response to the impedance falling below a predetermined threshold. A hydrophobic polymeric plug is disposed between the inner conductive tube and the polymeric tube in close proximity to a distal end of the polymeric tube so as to prevent fluid from entering between the inner conductive tube and the polymeric tube.
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Boger David L.
Jaichandra Doraiswami
Jaworski Donald L.
Perry Joseph E.
Bayer Corporation
Coe Roger N.
Snay Jeffrey R.
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