Flow through electroporation method

Details Flow through electroporation method Flow through electroporation method

1994-10-12

1996-08-13

Yasko, John D.

Surgery

Blood drawn and replaced or treated and returned to body

604 49, 935 52, A61M 3500

Patent

active

055451306

ABSTRACT:
A flow through apparatus for implanting molecules into living blood cells of a patient, comprises a housing including an elongated flow through chamber having an inlet and an outlet at opposite ends thereof, a pair of elongated spaced apart parallel electrodes disposed between the inlet and the outlet for fluid to flow therebetween, a continuous flow shunt including a pump for withdrawing blood from a patient, passing it through the flow through chamber between the electrodes and returning it to the patient, apparatus for injecting a predetermined quantity of fluid medium carrying preselected molecules into the blood after it has been drawn from the patient and before it passes through said chamber, and an electrical source for applying a predetermined electric signal of a predetermined amplitude and duration to the electrodes for generating and repeatedly applying electric fields of a predetermined amplitude and duration to the flow of the mixture of blood and fluid medium in order to make the walls of preselected cells in the blood transiently permeable to permit molecules to enter the preselected cells without killing the cells.

REFERENCES:
patent: 4970154 (1990-11-01), Chang
patent: 5098843 (1992-03-01), Calvin
patent: 5128257 (1992-07-01), Baer
patent: 5464386 (1995-11-01), Hofmann

Affiliated with

Also associated with

Rating

Flow through electroporation method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Flow through electroporation method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Flow through electroporation method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1044772