Flow-inflated diffusion therapeutic delivery

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

Reexamination Certificate

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Reexamination Certificate

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08043258

ABSTRACT:
The present application includes devices, systems and methods for therapeutic agent delivery. A device in accord with the invention may include a first infusion lumen having a proximal end, a distal end, a longitudinal axis and a therapeutic agent. This device may also include an inflatable balloon in fluid communication with the first infusion lumen, the inflatable balloon having an exit outlet wherein the device is configured to exert pressure at a target site with an external surface of the balloon, the exerted pressure greater than a target pressure prior to the therapeutic agent exiting the inflatable balloon. A method in accord with the invention may include positioning a delivery device near an intended treatment site, injecting therapeutic agent through an infusion lumen into an inflatable balloon, and determining a target pressure at a target site by monitoring the blood pressure of a patient.

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International Preliminary Report on Patentability and Written Opinion, PCT/US2007/001691, Aug. 7, 2008.

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