Flow detection appartus and method

Details Flow detection appartus and method Flow detection appartus and method

1995-12-27

1998-04-07

Le, Long V.

Chemistry: analytical and immunological testing

Automated chemical analysis

With a continuously flowing sample or carrier stream

436 63, 436 69, 436174, 436179, 436164, 436165, 422 58, 422 63, 422 73, 422 81, 422 8205, 422102, G01N 3386, G01N 2103

Patent

active

057364044

ABSTRACT:
Fluid sample tester assembly (12) comprises a cartridge (6) having a pressure chamber (22) and entrance port (20) connected by a passageway (24). An analyte reagent (36) is positioned along the fluid passageway so that when a liquid sample (28) is drawn through the entrance port into the passageway, the analyte reagent mixes with the sample. The sample is preferably drawn into the cartridge by temporarily reducing the volume of the pressure chamber, applying the sample to the entrance port and then returning the pressure chamber to its initial volume; this can also be done by heating the chamber, contacting the sample and then cooling the chamber. The end of the sample defines a boundary surface (30) along the fluid passageway. Positive and negative pressure is applied to the sample to cause the boundary surface to oscillate within the passageway. The position of the boundary surface is continuously monitored so that continuous boundary position data is obtained and is analyzed to obtain a flow-related characteristic, typically speed of coagulation, of the sample.

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