Flow cell facilitating precise delivery of reagent to a...

Chemistry: analytical and immunological testing – Automated chemical analysis – With a continuously flowing sample or carrier stream

Reexamination Certificate

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Details

C436S043000, C436S053000, C436S174000, C436S180000, C422S068100, C422S091000, C422S105000

Reexamination Certificate

active

07858372

ABSTRACT:
The present invention is a flow cell and method for use in microfluidic analyses that presents highly discrete and small volumes of fluid to isolated locations on a two-dimensional surface contained within an open fluidic chamber defined by the flow cell that has physical dimensions such that laminar style flow occurs for fluids flowing through the chamber. This process of location specific fluid addressing within the flow cell is facilitated by combining components of hydrodynamic focusing with site specific cell evacuation. The process does not require the use of physical barriers within the flow cell or mechanical valves to control the paths of fluid movement.

REFERENCES:
patent: 7160730 (2007-01-01), Bach et al.
patent: 2003/0206832 (2003-11-01), Thiebaud et al.
patent: 2004/0101870 (2004-05-01), Caubet et al.
patent: WO 00/56444 (2000-09-01), None
patent: WO00/56444 (2000-09-01), None
patent: WO 00/56444 (2000-09-01), None
patent: WO 02/25243 (2002-03-01), None
patent: WO/03/002985 (2003-01-01), None
patent: WO 03/079017 (2003-09-01), None
patent: WO 2005/024411 (2005-03-01), None
patent: WO/2006/050617 (2006-05-01), None
patent: WO 2006/050617 (2006-05-01), None

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