Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1987-08-07
1989-05-16
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530380, 530381, 530387, 530413, 530384, 530389, 530417, 530830, 530815, 530816, 530415, 436532, 436535, 424101, C07K 320, C07K 318, C07K 1708, C07K 1506
Patent
active
048311189
ABSTRACT:
The present invention is a protein purification column comprising an organic substrate matrix having low reactivity to proteins, said matrix being capable of maintaining monoclonal antibodies attached thereto in an external configuration and preventing interaction with the protein to be bound to the antibody, and a monoclonal antibody attached to the substrate, the monoclonal antibody having a specific affinity for the protein to be isolated.
The present invention also is a method for isolating and purifying specific protein from a solution, wherein
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Fulcher Carol A.
Zimmerman Theodore S.
Kushan Jeff P.
Moskowitz Margaret
Scripps Clinic and Research Foundation
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