Flourescence intramolecular energy transfer conjugate compositio

Details Flourescence intramolecular energy transfer conjugate compositio Flourescence intramolecular energy transfer conjugate compositio

1991-09-19

1993-10-19

Scheiner, Toni R.

Chemistry: analytical and immunological testing

Optical result

With fluorescence or luminescence

436 71, 436 95, 436164, 436536, 436537, 436501, 435 4, 435 11, 435 14, 435 15, G01N 2164, G01N 2180, C12Q 100

Patent

active

052544770

ABSTRACT:
A variety of conjugated compositions and methods for the detection of an analyte of interest in a fluid sample is provided which relies upon an intramolecular energy transfer between a conjugated fluorophore and a chromophoric light-absorbing ligand for qualitative and quantitative results. The detection methods preferably employ fiber optic sensors in combination with analyte-insensitive fluorophores and analyte-sensitive absorber ligands in conjugated form. The methods and compositions rely upon the ability of the absorbing ligands to absorb energy which is transferred non-radiatively by the fluorophore when in an excited state.

REFERENCES:
patent: 5143853 (1992-09-01), Walt

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