Floating system for oral therapy

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

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Details

424443, 424464, 424465, 424468, 424489, A61K 922, A61M 3100

Patent

active

056268769

ABSTRACT:
The invention relates to a floatable, oral, therapeutic system, in which a lengthening of the gastrointestinal residence time of medicaments and a controlled delivery thereof are achieved by systems, which are specifically lighter than the gastric fluid, float on the latter and can only with difficulty reach the lower-lying pylorus, said system using at least one structural element with cavities or voids, such as foams or hollow bodies.

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Lippold et al. In-Vivo-Prufung einer Multipartikularen Retard-Schwimmarzneiform. European Journal Pharm. Biopharm. 1991, vol. 37, No. 4, pp. 254-261.

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