Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Patent
1998-11-30
2000-04-11
Redding, David A.
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
4352883, 4352884, 4353052, 4353054, C12M 300
Patent
active
060487232
ABSTRACT:
A cell culture plate having a flexible membrane sandwiched between a base and a body. Each of the base and body have a plurality of mutually aligned openings. A wall surrounds each opening in the body thereby forming a cell culture well with a portion of the membrane functioning as the floor of the well. When a pressure differential is applied to the underside of the membrane, the membrane stretches, inducing strain on cells cultured thereon. The cell culture plate is sealingly positioned within a recess of a baseplate. An opening defined in the recess communicates with a pressure supply and provides fluid access to the cell culture plate underside to induce the pressure differential thereon.
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Flexcell International Corporation
Redding David A.
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