Flexible amphiphilic microbubbles for ultrasound

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Ultrasound contrast agent

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Details

424 951, 424 952, 424450, 12866702, A61B 813

Patent

active

055674135

ABSTRACT:
The invention relates to diagnostic ultrasound contrast agents comprising vesicles comprising an amphiphilic phospholipid material capable of formation of gas-containing vesicles wherein the vesicles contain gas which comprises a low molecular weight fluorinated hydrocarbon.

REFERENCES:
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patent: 5271928 (1993-12-01), Schneider et al.
patent: 5362478 (1994-11-01), Desai et al.
patent: 5425366 (1995-06-01), Reinhardt et al.
Juliano et al., Biochim. Biophys. Acta 812(1):42-48 (1985).

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