Flea protease proteins, nucleic acid molecules, and uses thereof

Details Flea protease proteins, nucleic acid molecules, and uses thereof Flea protease proteins, nucleic acid molecules, and uses thereof

1998-01-08

2000-12-05

Allen, Marianne P.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

435212, C12N 948, C12N 950

Patent

active

061565563

ABSTRACT:
The present invention relates to flea serine protease proteins and flea cysteine protease proteins; to flea serine protease and cysteine protease nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or cysteine protease activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.

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